Pub. Date : 2012 Jun 29
PMID : 22579474
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | interferon alpha 1 | Homo sapiens |
| 2 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | TANK binding kinase 1 | Homo sapiens |
| 3 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | TANK binding kinase 1 | Homo sapiens |
| 4 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | interferon regulatory factor 3 | Homo sapiens |
| 5 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | interferon regulatory factor 3 | Homo sapiens |
| 6 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | interferon alpha 1 | Homo sapiens |
| 7 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | TANK binding kinase 1 | Homo sapiens |
| 8 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | TANK binding kinase 1 | Homo sapiens |
| 9 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | interferon regulatory factor 3 | Homo sapiens |
| 10 | STING is an essential signaling molecule for DNA and cyclic di-GMP (c-di-GMP)-mediated type I interferon (IFN) production via TANK-binding kinase 1 (TBK1) and interferon regulatory factor 3 (IRF3) pathway. | bis(3',5')-cyclic diguanylic acid | interferon regulatory factor 3 | Homo sapiens |
| 11 | Binding of c-di-GMP enhanced interaction of a shorter construct of STING CTD (residues 139-344) with TBK1. | bis(3',5')-cyclic diguanylic acid | TANK binding kinase 1 | Homo sapiens |
| 12 | This study provides a glimpse into the unique architecture of STING and sheds light on the mechanism of c-di-GMP-mediated TBK1 signaling. | bis(3',5')-cyclic diguanylic acid | TANK binding kinase 1 | Homo sapiens |