Pub. Date : 2014 Jul-Aug
PMID : 24874800
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Polyphosphate, cyclic AMP, guanosine tetraphosphate, and c-di-GMP reduce in vitro Lon activity. | bis(3',5')-cyclic diguanylic acid | lon peptidase 1, mitochondrial | Homo sapiens |
| 2 | Since we found that Lon has several putative cyclic diguanylate (c-di-GMP) binding sites and since Lon binds polyphosphate (polyP) and lipid polysaccharide, we hypothesized that Lon has an affinity for phosphate-based molecules that might regulate its activity. | bis(3',5')-cyclic diguanylic acid | lon peptidase 1, mitochondrial | Homo sapiens |
| 3 | Since we found that Lon has several putative cyclic diguanylate (c-di-GMP) binding sites and since Lon binds polyphosphate (polyP) and lipid polysaccharide, we hypothesized that Lon has an affinity for phosphate-based molecules that might regulate its activity. | bis(3',5')-cyclic diguanylic acid | lon peptidase 1, mitochondrial | Homo sapiens |
| 4 | Inhibition of in vitro Lon activity occurred for polyP, cAMP, ppGpp, and c-di-GMP. | bis(3',5')-cyclic diguanylic acid | lon peptidase 1, mitochondrial | Homo sapiens |
| 5 | We also demonstrated by HPLC that Lon is able to bind c-di-GMP. | bis(3',5')-cyclic diguanylic acid | lon peptidase 1, mitochondrial | Homo sapiens |