Pub. Date : 2014 Jun 28
PMID : 24727060
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The induction of IFN-beta from c-di-GMP liposomes was inhibited by adding BX795, a TBK1 inhibitor, indicating that the production of IFN-beta caused the activation of the STING-TBK1 pathway. | bis(3',5')-cyclic diguanylic acid | interferon beta 1, fibroblast | Mus musculus |
| 2 | It is thought that c-di-GMP is recognized by ATP dependent RNA helicase (DDX41) in the cytosol, forms a complex with the Stimulator of interferon genes protein (STING), triggers a signal via the tank binding kinase 1-interferon regulatory factor 3 (TBK1-IRF3) pathway and induces the production of type I interferons. | bis(3',5')-cyclic diguanylic acid | DEAD box helicase 41 | Mus musculus |
| 3 | It is thought that c-di-GMP is recognized by ATP dependent RNA helicase (DDX41) in the cytosol, forms a complex with the Stimulator of interferon genes protein (STING), triggers a signal via the tank binding kinase 1-interferon regulatory factor 3 (TBK1-IRF3) pathway and induces the production of type I interferons. | bis(3',5')-cyclic diguanylic acid | stimulator of interferon response cGAMP interactor 1 | Mus musculus |
| 4 | It is thought that c-di-GMP is recognized by ATP dependent RNA helicase (DDX41) in the cytosol, forms a complex with the Stimulator of interferon genes protein (STING), triggers a signal via the tank binding kinase 1-interferon regulatory factor 3 (TBK1-IRF3) pathway and induces the production of type I interferons. | bis(3',5')-cyclic diguanylic acid | stimulator of interferon response cGAMP interactor 1 | Mus musculus |
| 5 | It is thought that c-di-GMP is recognized by ATP dependent RNA helicase (DDX41) in the cytosol, forms a complex with the Stimulator of interferon genes protein (STING), triggers a signal via the tank binding kinase 1-interferon regulatory factor 3 (TBK1-IRF3) pathway and induces the production of type I interferons. | bis(3',5')-cyclic diguanylic acid | TANK-binding kinase 1 | Mus musculus |
| 6 | It is thought that c-di-GMP is recognized by ATP dependent RNA helicase (DDX41) in the cytosol, forms a complex with the Stimulator of interferon genes protein (STING), triggers a signal via the tank binding kinase 1-interferon regulatory factor 3 (TBK1-IRF3) pathway and induces the production of type I interferons. | bis(3',5')-cyclic diguanylic acid | interferon regulatory factor 3 | Mus musculus |
| 7 | The induction of IFN-beta from c-di-GMP liposomes was inhibited by adding BX795, a TBK1 inhibitor, indicating that the production of IFN-beta caused the activation of the STING-TBK1 pathway. | bis(3',5')-cyclic diguanylic acid | interferon beta 1, fibroblast | Mus musculus |
| 8 | The induction of IFN-beta from c-di-GMP liposomes was inhibited by adding BX795, a TBK1 inhibitor, indicating that the production of IFN-beta caused the activation of the STING-TBK1 pathway. | bis(3',5')-cyclic diguanylic acid | TANK-binding kinase 1 | Mus musculus |
| 9 | The induction of IFN-beta from c-di-GMP liposomes was inhibited by adding BX795, a TBK1 inhibitor, indicating that the production of IFN-beta caused the activation of the STING-TBK1 pathway. | bis(3',5')-cyclic diguanylic acid | stimulator of interferon response cGAMP interactor 1 | Mus musculus |
| 10 | The induction of IFN-beta from c-di-GMP liposomes was inhibited by adding BX795, a TBK1 inhibitor, indicating that the production of IFN-beta caused the activation of the STING-TBK1 pathway. | bis(3',5')-cyclic diguanylic acid | TANK-binding kinase 1 | Mus musculus |
| 11 | C-di-GMP liposomes also showed significantly higher levels of expression of CD80, CD86 and MHC class I. | bis(3',5')-cyclic diguanylic acid | CD80 antigen | Mus musculus |
| 12 | C-di-GMP liposomes also showed significantly higher levels of expression of CD80, CD86 and MHC class I. | bis(3',5')-cyclic diguanylic acid | CD86 antigen | Mus musculus |