Pub. Date : 2014 Sep
PMID : 24913717
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Low doses of c-di-GMP significantly increased the production of IL12 by MDSCs, in correlation with improved T-cell responses to Mage-b, whereas a high dose of c-di-GMP (range, 0.3-3 mmol/L) activated caspase-3 in the 4T1 tumor cells and killed the tumor cells directly. | bis(3',5')-cyclic diguanylic acid | caspase 3 | Mus musculus |
| 2 | This finding correlated with a mechanism of improved CD8 T-cell responses to tumor-associated antigens (TAA) Mage-b and Survivin, most likely through cross-presentation of these TAAs from c-di-GMP-killed 4T1 tumor cells, and through c-di-GMP-activated TAA-specific T cells. | bis(3',5')-cyclic diguanylic acid | baculoviral IAP repeat-containing 5 | Mus musculus |
| 3 | This finding correlated with a mechanism of improved CD8 T-cell responses to tumor-associated antigens (TAA) Mage-b and Survivin, most likely through cross-presentation of these TAAs from c-di-GMP-killed 4T1 tumor cells, and through c-di-GMP-activated TAA-specific T cells. | bis(3',5')-cyclic diguanylic acid | baculoviral IAP repeat-containing 5 | Mus musculus |