| 1 | 3345759 | Interaction of a spin-labelled cholesterol derivative with the cytochrome P-450scc active site. | Eur J Biochem | 1988 Feb 15 |
1 |
| 2 | 9840430 | Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine. | Naunyn Schmiedebergs Arch Pharmacol | 1998 Nov |
4 |
| 3 | 10359460 | Characterization of the human hepatic cytochromes P450 involved in the in vitro oxidation of clozapine. | Chem Biol Interact | 1999 Apr 1 |
4 |
| 4 | 14751426 | Effects of clozapine and its metabolites on the 5-HT2 receptor system in cortical and hippocampal cells in vitro. | Prog Neuropsychopharmacol Biol Psychiatry | 2004 Mar |
3 |
| 5 | 16184070 | Examining concentration-dependent toxicity of clozapine: role of therapeutic drug monitoring. | J Psychiatr Pract | 2005 Sep |
2 |
| 6 | 18809730 | Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes. | Drug Metab Dispos | 2008 Dec |
2 |
| 7 | 23303063 | A Gαs DREADD mouse for selective modulation of cAMP production in striatopallidal neurons. | Neuropsychopharmacology | 2013 Apr |
4 |
| 8 | 23426689 | Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. | J Neurosci | 2013 Feb 20 |
1 |
| 9 | 24042499 | Modulation of the autonomic nervous system and behaviour by acute glial cell Gq protein-coupled receptor activation in vivo. | J Physiol | 2013 Nov 15 |
1 |
| 10 | 24525710 | Chemogenetic inactivation of ventral hippocampal glutamatergic neurons disrupts consolidation of contextual fear memory. | Neuropsychopharmacology | 2014 Jul |
2 |
| 11 | 24951857 | Concurrent and robust regulation of feeding behaviors and metabolism by orexin neurons. | Neuropharmacology | 2014 Oct |
3 |
| 12 | 25978516 | Hindbrain Catecholamine Neurons Activate Orexin Neurons During Systemic Glucoprivation in Male Rats. | Endocrinology | 2015 Aug |
2 |
| 13 | 26394842 | Pharmacogenetic stimulation of cholinergic pedunculopontine neurons reverses motor deficits in a rat model of Parkinson's disease. | Mol Neurodegener | 2015 Sep 23 |
1 |
| 14 | 26693173 | Agonist-evoked Ca<sup>2+</sup> signaling in enteric glia drives neural programs that regulate intestinal motility in mice. | Cell Mol Gastroenterol Hepatol | 2015 Nov 1 |
1 |
| 15 | 27030736 | DREADD-induced activation of subfornical organ neurons stimulates thirst and salt appetite. | J Neurophysiol | 2016 Jun 1 |
1 |
| 16 | 27184631 | Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase. | J Neuroinflammation | 2016 May 16 |
1 |
| 17 | 27206427 | Nucleus incertus promotes cortical desynchronization and behavioral arousal. | Brain Struct Funct | 2017 Jan |
1 |
| 18 | 27320963 | What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse? | Toxicol Lett | 2016 Sep 6 |
1 |
| 19 | 27428822 | Alleviating Bone Cancer-induced Mechanical Hypersensitivity by Inhibiting Neuronal Activity in the Anterior Cingulate Cortex. | Anesthesiology | 2016 Oct |
1 |
| 20 | 27853934 | Evaluation of In Vitro Cytochrome P450 Inhibition and In Vitro Fate of Structurally Diverse N-Oxide Metabolites: Case Studies with Clozapine, Levofloxacin, Roflumilast, Voriconazole and Zopiclone. | Eur J Drug Metab Pharmacokinet | 2017 Aug |
3 |
| 21 | 28073937 | Activity of <i>Tachykinin1</i>-Expressing <i>Pet1</i> Raphe Neurons Modulates the Respiratory Chemoreflex. | J Neurosci | 2017 Feb 15 |
4 |
| 22 | 28322236 | The Role of Mesolimbic Reward Neurocircuitry in Prevention and Rescue of the Activity-Based Anorexia (ABA) Phenotype in Rats. | Neuropsychopharmacology | 2017 Nov |
2 |
| 23 | 28340122 | Potential Role of Patients' CYP3A-Status in Clozapine Pharmacokinetics. | Int J Neuropsychopharmacol | 2017 Jul 1 |
1 |
| 24 | 28363838 | Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet. | Physiol Behav | 2017 Jul 1 |
2 |
| 25 | 28386207 | Activation of the ventral tegmental area increased wakefulness in mice. | Sleep Biol Rhythms | 2017 |
1 |
| 26 | 28472396 | Chronic activation of hypothalamic oxytocin neurons improves cardiac function during left ventricular hypertrophy-induced heart failure. | Cardiovasc Res | 2017 Sep 1 |
1 |
| 27 | 28495999 | <i>β</i>-Arrestin-Mediated Regulation of the Human <i>Ether-a-go-go</i>-Related Gene Potassium Channel. | Mol Pharmacol | 2017 Aug |
1 |
| 28 | 29155491 | Variation in the Response of Clozapine Biotransformation Pathways in Human Hepatic Microsomes to CYP1A2- and CYP3A4-selective Inhibitors. | Basic Clin Pharmacol Toxicol | 2018 Apr |
2 |
| 29 | 29218003 | Eye-Drops for Activation of DREADDs. | Front Neural Circuits | 2017 |
1 |
| 30 | 29485117 | Acute pharmacogenetic activation of medial prefrontal cortex excitatory neurons regulates anxiety-like behaviour. | J Biosci | 2018 Mar |
1 |
| 31 | 29635888 | Repetitive and compulsive-like behaviors lead to cognitive dysfunction in Disc1<sup>Δ2-3/Δ2-3</sup> mice. | Genes Brain Behav | 2018 Nov |
1 |
| 32 | 29668112 | Pharmacogenetic Manipulation of the Nucleus Accumbens Alters Binge-Like Alcohol Drinking in Mice. | Alcohol Clin Exp Res | 2018 May |
1 |
| 33 | 29754898 | Replay of Episodic Memories in the Rat. | Curr Biol | 2018 May 21 |
2 |
| 34 | 29874094 | Activation of catecholamine neurons in the ventral medulla reduces CCK-induced hypophagia and c-Fos activation in dorsal medullary catecholamine neurons. | Am J Physiol Regul Integr Comp Physiol | 2018 Sep 1 |
3 |
| 35 | 30203849 | Regulating nociceptive transmission by VGluT2-expressing spinal dorsal horn neurons. | J Neurochem | 2018 Nov |
1 |
| 36 | 30321287 | DREADD technology reveals major impact of Gq signalling on cardiac electrophysiology. | Cardiovasc Res | 2019 May 1 |
1 |
| 37 | 30914732 | Effect of oestrogen-dependent vasopressin on HPA axis in the median eminence of female rats. | Sci Rep | 2019 Mar 26 |
1 |
| 38 | 30923740 | Selectively Inhibiting the Median Preoptic Nucleus Attenuates Angiotensin II and Hyperosmotic-Induced Drinking Behavior and Vasopressin Release in Adult Male Rats. | eNeuro | 2019 Mar-Apr |
1 |
| 39 | 30984001 | Attenuation of Novelty-Induced Hyperactivity of <i>Gria1-/-</i> Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics. | Front Pharmacol | 2019 |
1 |
| 40 | 31470043 | Chemogenetic manipulation of parasympathetic neurons (DMV) regulates feeding behavior and energy metabolism. | Neurosci Lett | 2019 Nov 1 |
1 |
| 41 | 31498301 | Non-invasive Strategies for Chronic Manipulation of DREADD-controlled Neuronal Activity. | J Vis Exp | 2019 Aug 25 |
1 |
| 42 | 31608439 | Long-term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy. | Epilepsia | 2019 Nov |
1 |
| 43 | 31645362 | Chemogenetic Activation of Excitatory Neurons Alters Hippocampal Neurotransmission in a Dose-Dependent Manner. | eNeuro | 2019 Nov/Dec |
1 |
| 44 | 31752398 | Transient Chemogenetic Inhibition of D1-MSNs in the Dorsal Striatum Enhances Methamphetamine Self-Administration. | Brain Sci | 2019 Nov 19 |
10 |
| 45 | 32513661 | Chemogenetic Suppression of GnRH Neurons during Pubertal Development Can Alter Adult GnRH Neuron Firing Rate and Reproductive Parameters in Female Mice. | eNeuro | 2020 May/Jun |
2 |
| 46 | 32636748 | Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain. | Front Pharmacol | 2020 |
1 |
| 47 | 34004259 | Abnormalities in the composition of the gut microbiota in mice after repeated administration of DREADD ligands. | Brain Res Bull | 2021 Aug |
2 |
| 48 | 34607024 | Sexually dimorphic muscarinic acetylcholine receptor modulation of contextual fear learning in the dentate gyrus. | Neurobiol Learn Mem | 2021 Nov |
1 |
| 49 | 34654906 | Characterization of DREADD receptor expression and function in rhesus macaques trained to discriminate ethanol. | Neuropsychopharmacology | 2022 Mar |
1 |
| 50 | 34811712 | Activation of Lateral Parabrachial Nucleus (LPBn) PACAP-Expressing Projection Neurons to the Bed Nucleus of the Stria Terminalis (BNST) Enhances Anxiety-like Behavior. | J Mol Neurosci | 2022 Mar |
1 |