Title : Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase.

Pub. Date : 2016 May 16

PMID : 27184631






1 Functional Relationships(s)
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1 The purpose of this study was to explore the neuroprotective effects of clozapine metabolites clozapine N-oxide (CNO) and N-desmethylclozapine (NDC), as well as their propensity to cause neutropenia. clozapine N-oxide biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino Mus musculus