Title : Examining concentration-dependent toxicity of clozapine: role of therapeutic drug monitoring.

Pub. Date : 2005 Sep

PMID : 16184070






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 These are CYP1A2, the primary enzyme involved in converting clozapine to norclozapine, and CYP3A4, the primary enzyme involved in converting clozapine to clozapine-N-oxide. clozapine N-oxide cytochrome P450 family 1 subfamily A member 2 Homo sapiens
2 These are CYP1A2, the primary enzyme involved in converting clozapine to norclozapine, and CYP3A4, the primary enzyme involved in converting clozapine to clozapine-N-oxide. clozapine N-oxide cytochrome P450 family 3 subfamily A member 4 Homo sapiens