Docetaxel






2696 Article(s)
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51 10576649 The acridonecarboxamide GF120918 potently reverses P-glycoprotein-mediated resistance in human sarcoma MES-Dx5 cells. Br J Cancer 1999 Nov 2
52 10601617 Clofazimine and B4121 sensitize an intrinsically resistant human colon cancer cell line to P-glycoprotein substrates. Oncol Rep 2000 Jan-Feb 3
53 10604261 Mechanisms of action of taxanes in prostate cancer. Semin Oncol 1999 Oct 1
54 10604264 A phase II trial of docetaxel (Taxotere) in hormone-refractory prostate cancer: correlation of antitumor effect to phosphorylation of Bcl-2. Semin Oncol 1999 Oct 2
55 10606283 Targeting bcl-2 gene to delay androgen-independent progression and enhance chemosensitivity in prostate cancer using antisense bcl-2 oligodeoxynucleotides. Urology 1999 Dec 2
56 10615229 Docetaxel compared with sequential methotrexate and 5-fluorouracil in patients with advanced breast cancer after anthracycline failure: a randomised phase III study with crossover on progression by the Scandinavian Breast Group. Eur J Cancer 1999 Aug 1
57 10639573 NADPH/quinone oxidoreductase is a priority target of glioblastoma chemotherapy. Int J Oncol 2000 Feb 3
58 10665657 Interaction of docetaxel ("Taxotere") with human P-glycoprotein. Jpn J Cancer Res 1999 Dec 14
59 10675076 Colitis associated with docetaxel-based chemotherapy in patients with metastatic breast cancer. Lancet 2000 Jan 22 1
60 10687988 Dexamethasone does not significantly contribute to the response rate of docetaxel and estramustine in androgen independent prostate cancer. J Urol 2000 Mar 1
61 10697568 Taxotere activates transcription factor AP-1 in association with apoptotic cell death in gastric cancer cell lines. Anticancer Res 1999 Nov-Dec 8
62 10699926 Late apoptotic effects of taxanes on K562 erythroleukemia cells: apoptosis is delayed upstream of caspase-3 activation. Int J Cancer 2000 Feb 15 3
63 10699953 Resistance to taxanes is induced by c-erbB-2 overexpression in human MCF-10A mammary epithelial cells and is blocked by combined treatment with an antisense oligonucleotide targeting type I protein kinase A. Int J Cancer 2000 Mar 1 2
64 10737719 Non-ionic detergent Tween 80 modulates VP-16 resistance in classical multidrug resistant K562 cells via enhancement of VP-16 influx. Cancer Lett 2000 Feb 28 2
65 10767372 Cell cycle status and apoptosis of hematopoietic progenitor cells released into the peripheral blood after taxanes and granulocyte colony-stimulating factor in breast cancer patients. Oncol Rep 2000 May-Jun 1
66 10769693 Enhancement of chemotherapeutic agents induced-apoptosis associated with activation of c-Jun N-terminal kinase 1 and caspase 3 (CPP32) in bax-transfected gastric cancer cells. Anticancer Res 2000 Jan-Feb 2
67 10778948 The effect of an individual's cytochrome CYP3A4 activity on docetaxel clearance. Clin Cancer Res 2000 Apr 5
68 10810400 Single agent docetaxel plus granulocyte-colony stimulating factor (G-CSF) in previously treated patients with advanced non small cell lung cancer. A phase II study and review of the literature. Anticancer Res 2000 Mar-Apr 1
69 10810934 Docetaxel (Taxotere) in HER-2-positive patients and in combination with trastuzumab (Herceptin). Semin Oncol 2000 Apr 2
70 10811471 Synergistic effects of adenovirus expressing wild-type p53 on chemosensitivity of non-small cell lung cancer cells. Cancer Gene Ther 2000 Apr 1
71 10829051 Correlation between docetaxel clearance and estimated cytochrome P450 activity by urinary metabolite of exogenous cortisol. J Clin Oncol 2000 Jun 2
72 10871820 Phase I/II dose escalation study of docetaxel and carboplatin combination supported with amifostine and GM-CSF in patients with incomplete response following docetaxel chemo-radiotherapy: additional chemotherapy enhances regression of residual cancer. Med Oncol 2000 May 1
73 10914699 Role of intestinal P-glycoprotein in the plasma and fecal disposition of docetaxel in humans. Clin Cancer Res 2000 Jul 3
74 10945505 Proteolysis of microtubule associated protein 2 and sensitivity of pancreatic tumours to docetaxel. Br J Cancer 2000 Aug 2
75 10948319 Enhancement of immunohistochemical reactivity for thymidine phosphorylase in breast carcinoma cells after administration of docetaxel as a neoadjuvant chemotherapy in advanced breast cancer patients. Oncol Rep 2000 Sep-Oct 5
76 10955790 Predictive value of p53, mdm-2, p21, and mib-1 for chemotherapy response in advanced breast cancer. Clin Cancer Res 2000 Aug 2
77 10955859 Frontline treatment of advanced gastric cancer with docetaxel and granulocyte colony-stimulating factor (G-CSF): a phase II trial. Am J Clin Oncol 2000 Aug 1
78 10963840 Second-line chemotherapy for recurrent non-small cell lung cancer: do new agents make a difference? Lung Cancer 2000 Aug 2
79 10999771 In vitro evaluation of schedule-dependent interactions between docetaxel and doxorubicin against human breast and ovarian cancer cells. Clin Cancer Res 2000 Sep 2
80 11001384 Differential impact of Raf-1 kinase activity on tumor cell resistance to paclitaxel and docetaxel. Anticancer Drugs 2000 Jul 3
81 11002234 Docetaxel-induced lymphopenia in patients with solid tumors: a prospective phenotypic analysis. Cancer 2000 Sep 15 5
82 11019836 Docetaxel effectively mobilizes peripheral blood CD34+ cells. Bone Marrow Transplant 2000 Sep 3
83 11029783 Regulation of interleukin-6 secretion from breast cancer cells and its clinical implications. Breast Cancer 2000 2
84 11057324 [Antitumor activity of UFT and docetaxel on human breast carcinoma xenografts]. Gan To Kagaku Ryoho 2000 Oct 1
85 11097380 Cytotoxicity of cyclophosphamide, paclitaxel, and docetaxel for tumor cell lines in vitro: effects of concentration, time and cytochrome P450-catalyzed metabolism. Arch Toxicol 2000 Oct 6
86 11102737 Modulation of oral bioavailability of anticancer drugs: from mouse to man. Eur J Pharm Sci 2000 Dec 2
87 11103243 [Effectiveness of docetaxel plus cisplatin in large cell lung cancer showing little response to prior chemotherapy with MVP]. Gan To Kagaku Ryoho 2000 Nov 1
88 11124653 Chemotherapy-induced noncardiogenic pulmonary edema related to gemcitabine plus docetaxel combination with granulocyte colony-stimulating factor support. Respiration 2000 1
89 11138457 Phase I study of docetaxel and topotecan in patients with solid tumors. Cancer Chemother Pharmacol 2000 2
90 11156248 Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. Clin Cancer Res 2000 Dec 1
91 11160641 Human CYP1B1 and anticancer agent metabolism: mechanism for tumor-specific drug inactivation? J Pharmacol Exp Ther 2001 Feb 1
92 11177597 Mobilization of peripheral blood stem cells in high-risk breast cancer patients using G-CSF after standard dose docetaxel. J Hematother Stem Cell Res 2000 Dec 2
93 11181682 Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel. J Clin Oncol 2001 Feb 15 5
94 11182366 Different docetaxel-induced apoptotic pathways are present in prostate cancer cell lines LNCaP and PC-3. Urology 2001 Feb 6
95 11212279 Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels. Cancer Res 2001 Jan 15 3
96 11265409 [A case of recurrent breast cancer successfully treated with docetaxel]. Gan To Kagaku Ryoho 2001 Mar 1
97 11309294 The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. Cancer Res 2001 Apr 15 6
98 11329060 The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux. Nat Med 2001 May 1
99 11329786 [A case of docetaxel-resistant breast cancer responsive to paclitaxel therapy]. Gan To Kagaku Ryoho 2001 Apr 1
100 11335876 Efficacy of monochemotherapy with docetaxel (taxotere) in relation to prolactin secretion in heavily pretreated metastatic breast cancer. Neuro Endocrinol Lett 2001 2