Title : Correlation between docetaxel clearance and estimated cytochrome P450 activity by urinary metabolite of exogenous cortisol.

Pub. Date : 2000 Jun

PMID : 10829051






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Cortisol is metabolized by this enzyme and excreted as 6-beta-hydroxycortisol (6beta-OHF) and free-cortisol (FC) in urine, and docetaxel is also metabolized by hepatic CYP3A4 enzyme. Docetaxel cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 The correlation between docetaxel pharmacokinetics and estimated interpatient variability of CYP3A4 activity with the application of our method was assessed. Docetaxel cytochrome P450 family 3 subfamily A member 4 Homo sapiens