Pub. Date : 2001 Feb
PMID : 11182366
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Different docetaxel-induced apoptotic pathways are present in prostate cancer cell lines LNCaP and PC-3. | Docetaxel | chromobox 8 | Homo sapiens |
| 2 | OBJECTIVES: To investigate the molecular machinery of docetaxel (Taxotere)-initiated death signaling on prostate cancer cell lines LNCaP and PC-3. | Docetaxel | chromobox 8 | Homo sapiens |
| 3 | OBJECTIVES: To investigate the molecular machinery of docetaxel (Taxotere)-initiated death signaling on prostate cancer cell lines LNCaP and PC-3. | Docetaxel | chromobox 8 | Homo sapiens |
| 4 | Taxotere has demonstrated induction of cell death in LNCaP and PC-3 cells. | Docetaxel | chromobox 8 | Homo sapiens |
| 5 | METHODS: The prostate cancer cell lines, LNCaP and PC-3, were treated with 40 nM Taxotere for various lengths of time (0.5 to 24 hours). | Docetaxel | chromobox 8 | Homo sapiens |
| 6 | CONCLUSIONS: In this study, we demonstrated two distinctly different Taxotere-induced apoptotic pathways in LNCaP and PC-3 cells that may be of clinical importance when treating prostate cancer. | Docetaxel | chromobox 8 | Homo sapiens |