| 1 |
30869126 | Recombinant dermatan sulfate is a potent activator of heparin cofactor II-dependent inhibition of thrombin. | 2019 Jun 1 |
1 |
| 2 |
29173042 | Antithrombin conformational modulation by D-myo-inositol 3,4,5,6-tetrakisphosphate (TMI), a novel scaffold for the development of antithrombotic agents. | 2018 Nov |
1 |
| 3 |
26548632 | Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes. | 2016 Jan |
1 |
| 4 |
22315264 | Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. | 2012 Feb |
1 |
| 5 |
22506762 | A method to cleave target molecules in a neocartilage. | 2012 |
1 |
| 6 |
22618708 | Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism. | 2012 Jul 12 |
2 |
| 7 |
23152789 | On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different. | 2012 |
1 |
| 8 |
21256835 | The dermatan sulfate-dependent anticoagulant pathway is mostly preserved in aneurysm and in severe atherosclerotic lesions while the heparan sulfate pathway is disrupted. | 2011 May 12 |
1 |
| 9 |
20002544 | Polyphosphate binds with high affinity to exosite II of thrombin. | 2010 Mar |
1 |
| 10 |
20670608 | Glycosaminoglycan-binding properties and kinetic characterization of human heparin cofactor II expressed in Escherichia coli. | 2010 Nov 15 |
3 |
| 11 |
20807657 | Glycosaminoglycans and activated contact system in cancer patient plasmas. | 2010 |
1 |
| 12 |
18571697 | Thrombin regulates vascular smooth muscle cell proteoglycan synthesis via PAR-1 and multiple downstream signalling pathways. | 2008 |
3 |
| 13 |
18574264 | Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). | 2008 Jun |
1 |
| 14 |
17222891 | Effect of oversulfated dermatan sulfate derivatives on platelet aggregation. | 2007 |
1 |
| 15 |
17658885 | Glycosaminoglycans as naturally occurring combinatorial libraries: developing a mass spectrometry-based strategy for characterization of anti-thrombin interaction with low molecular weight heparin and heparin oligomers. | 2007 Aug 15 |
1 |
| 16 |
16556679 | Heparin prevents programmed cell death in human trophoblast. | 2006 Apr |
1 |
| 17 |
14962227 | Prothrombin Shanghai: hypoprothrombinaemia caused by substitution of Gla29 by Gly. | 2004 Jan |
1 |
| 18 |
15078125 | Structural and conformational aspects of the anticoagulant and anti-thrombotic activity of heparin and dermatan sulfate. | 2004 |
4 |
| 19 |
15196911 | RNA aptamer to thrombin binds anion-binding exosite-2 and alters protease inhibition by heparin-binding serpins. | 2004 Jun 18 |
1 |
| 20 |
15292227 | Molecular mapping of the thrombin-heparin cofactor II complex. | 2004 Oct 8 |
2 |
| 21 |
15311269 | Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin. | 2004 Sep |
1 |
| 22 |
15320789 | Novel human plasma proteins, IHRP (acute phase protein) and PHBP (serine protease), which bind to glycosaminoglycans. | 2004 Jul |
1 |
| 23 |
15383472 | Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. | 2004 Sep |
1 |
| 24 |
12818259 | Additive thrombin inhibition by fast moving heparin and dermatan sulfate explains the anticoagulant effect of sulodexide, a natural mixture of glycosaminoglycans. | 2003 Mar 15 |
1 |
| 25 |
15013278 | Prolonged bleeding time induced by anticoagulant glycosaminoglycans in dogs is associated with the inhibition of thrombin-induced platelet aggregation. | 2003 |
1 |
| 26 |
11856753 | Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II promote intramolecular interactions during glycosaminoglycan binding and thrombin inhibition. | 2002 May 31 |
4 |
| 27 |
12169660 | Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism. | 2002 Aug 20 |
2 |
| 28 |
12413592 | Inhibition of a thrombin anion-binding exosite-2 mutant by the glycosaminoglycan-dependent serpins protein C inhibitor and heparin cofactor II. | 2002 Jul 15 |
1 |
| 29 |
13679662 | Dermatan sulphate as an antithrombotic drug. | 2002 Sep-Dec |
1 |
| 30 |
11323006 | Heparin cofactor II, antithrombin-beta and their complexes with thrombin in human tissues. | 2001 Mar 15 |
2 |
| 31 |
11460008 | In vitro interaction of C1-inhibitor with thrombin. | 2001 Jun |
1 |
| 32 |
11068038 | Effect of oligodeoxynucleotide thrombin aptamer on thrombin inhibition by heparin cofactor II and antithrombin. | 2000 Nov 3 |
1 |
| 33 |
11776053 | Basic and clinical study on the antithrombotic mechanism of glycosaminoglycan extracted from sea cucumber. | 2000 Aug |
2 |
| 34 |
10447213 | Specificity of glycosaminoglycan suppression of endothelin-1 production by human umbilical vein endothelial cells. | 1999 |
1 |
| 35 |
10574918 | Enhancement of heparin cofactor II anticoagulant activity. | 1999 Dec 3 |
2 |
| 36 |
9586576 | Increased anticoagulant activity of recombinant thrombomodulin modified with glycosaminoglycan. | 1998 Apr |
1 |
| 37 |
9597755 | The glycosylation sites and structural characteristics of oligosaccharides on recombinant human thrombomodulin. | 1998 Jan |
4 |
| 38 |
9692391 | Structural characterization and functional effects of a circulating heparan sulfate in a patient with hepatocellular carcinoma. | 1998 Aug |
1 |
| 39 |
9813026 | Role of thrombin anion-binding exosite-I in the formation of thrombin-serpin complexes. | 1998 Nov 20 |
1 |
| 40 |
8603018 | Thrombin-mediated activation of endogenous factor XI in plasma in the presence of physiological glycosaminoglycans occurs only with high concentrations of thrombin. | 1996 Feb |
2 |
| 41 |
8807725 | Pathophysiology of thromboembolism and its modulation by low-molecular-weight heparins. | 1996 |
1 |
| 42 |
8746633 | Characterization of recombinant heparin cofactor II expressed in insect cells. | 1995 Dec |
1 |
| 43 |
7806495 | Heparin cofactor II is regulated allosterically and not primarily by template effects. Studies with mutant thrombins and glycosaminoglycans. | 1994 Dec 30 |
5 |
| 44 |
8186357 | An overview of the mechanism of action of antithrombin and its inherited deficiency states. | 1994 Jan |
1 |
| 45 |
21244893 | Heparin cofactor II and thrombin Heparin-binding proteins linking hemostasis and inflammation. | 1994 May-Jun |
1 |
| 46 |
8339853 | Impaired fibrinolytic response to increased thrombin activation in type 1 diabetes mellitus: effects of the glycosaminoglycan sulodexide. | 1993 Mar-Apr |
1 |
| 47 |
8384442 | Role of the glycosaminoglycan component of thrombomodulin in its acceleration of the inactivation of single-chain urokinase-type plasminogen activator by thrombin. | 1993 Mar 15 |
1 |
| 48 |
8429008 | Inhibition of dysthrombins Quick I and II by heparin cofactor II and antithrombin. | 1993 Feb 15 |
3 |
| 49 |
8429040 | Mutagenesis of thrombin selectively modulates inhibition by serpins heparin cofactor II and antithrombin III. Interaction with the anion-binding exosite determines heparin cofactor II specificity. | 1993 Feb 15 |
4 |
| 50 |
8431448 | Specific glycosaminoglycans support the inhibition of thrombin by plasminogen activator inhibitor 1. | 1993 Feb 16 |
1 |