Title : Thrombin regulates vascular smooth muscle cell proteoglycan synthesis via PAR-1 and multiple downstream signalling pathways.

Pub. Date : 2008

PMID : 18571697






3 Functional Relationships(s)
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Compound Name
Protein Name
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1 Chemically cleaved glycosaminoglycan (GAG) chains analyzed by SDS-PAGE and size exclusion chromatography were larger for proteoglycans from thrombin treated cells. Glycosaminoglycans coagulation factor II, thrombin Homo sapiens
2 Chemically cleaved glycosaminoglycan (GAG) chains analyzed by SDS-PAGE and size exclusion chromatography were larger for proteoglycans from thrombin treated cells. Glycosaminoglycans coagulation factor II, thrombin Homo sapiens
3 Thus, thrombin has actions on VSMCs which increase the length and modify the sulfation pattern of GAG chains on proteoglycans in a manner that would enhance the binding of LDL. Glycosaminoglycans coagulation factor II, thrombin Homo sapiens