Pub. Date : 1993 Feb 15
PMID : 8429008
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Heparin cofactor II and antithrombin are plasma serine proteinase inhibitors whose ability to inhibit alpha-thrombin is accelerated by glycosaminoglycans. | Glycosaminoglycans | coagulation factor II, thrombin | Homo sapiens |
2 | We also found that heparin cofactor II formed a SDS-resistant bimolecular complex with Quick II and alpha-thrombin at similar rates and the rate of complex formation was accelerated in the presence of glycosaminoglycans. | Glycosaminoglycans | coagulation factor II, thrombin | Homo sapiens |
3 | The importance of heparin cofactor II as a thrombin regulator will depend upon its ability to interact with glycosaminoglycans and the functional availability of thrombin exosites. | Glycosaminoglycans | coagulation factor II, thrombin | Homo sapiens |