Title : Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes.

Pub. Date : 2016 Jan

PMID : 26548632






1 Functional Relationships(s)
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1 Here, we demonstrate that thrombin elicits dual transactivation-dependent signalling pathways to stimulate mRNA expression of glycosaminoglycan synthesizing enzymes chondroitin 4-O-sulfotransferase 1 and chondroitin sulfate synthase 1. Glycosaminoglycans coagulation factor II, thrombin Homo sapiens