Title : Increased anticoagulant activity of recombinant thrombomodulin modified with glycosaminoglycan.

Pub. Date : 1998 Apr

PMID : 9586576






1 Functional Relationships(s)
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1 In vitro, the activity of cleavage of fibrinogen by thrombin or prothrombinase activity was more potently depressed by GAG-UTM than by r-UTM, and the generation of activated protein C by TM-thrombin complex was accelerated by GAG modification. Glycosaminoglycans coagulation factor II, thrombin Homo sapiens