Title : Role of thrombin anion-binding exosite-I in the formation of thrombin-serpin complexes.

Pub. Date : 1998 Nov 20

PMID : 9813026






1 Functional Relationships(s)
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1 Site-directed mutagenesis was used to investigate the role of basic residues in the thrombin anion-binding exosite-I during formation of thrombin-antithrombin III (ATIII), thrombin-protease nexin 1 (PN1), and thrombin-heparin cofactor II (HCII) inhibitor complexes, in the absence and presence of glycosaminoglycans. Glycosaminoglycans coagulation factor II, thrombin Homo sapiens