Pub. Date : 2010 Nov 15
PMID : 20670608
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Irreversible inactivation of alpha-thrombin (T) by the serpin, heparin cofactor II (HCII), is accelerated by ternary complex formation with the glycosaminoglycans (GAGs) heparin and dermatan sulfate (DS). | Glycosaminoglycans | coagulation factor II, thrombin | Homo sapiens |
| 2 | Second-order rate constants for thrombin inactivation by recombinant and deglycosylated HCII were comparable, at optimal GAG concentrations that were lower than those for plasma HCII, consistent with its weaker GAG binding. | Glycosaminoglycans | coagulation factor II, thrombin | Homo sapiens |
| 3 | Second-order rate constants for thrombin inactivation by recombinant and deglycosylated HCII were comparable, at optimal GAG concentrations that were lower than those for plasma HCII, consistent with its weaker GAG binding. | Glycosaminoglycans | coagulation factor II, thrombin | Homo sapiens |