134 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 26681186 | Quinazolines as Apoptosis Inducers and Inhibitors: A Review of Patent Literature. | 2016 | 2 |
52 | 26763193 | Synthesis of p-O-Alkyl Salicylanilide Derivatives as Novel EGFR Inhibitors. | 2016 Feb | 1 |
53 | 26829280 | Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines. | 2016 Mar 3 | 2 |
54 | 26879314 | Novel morpholin-3-one fused quinazoline derivatives as EGFR tyrosine kinase inhibitors. | 2016 Mar 15 | 2 |
55 | 27102572 | EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen. | 2016 Jul | 1 |
56 | 27118497 | Facile and efficient synthesis and biological evaluation of 4-anilinoquinazoline derivatives as EGFR inhibitors. | 2016 Jun 1 | 1 |
57 | 27132165 | Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor. | 2016 Aug 8 | 2 |
58 | 27135370 | Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. | 2016 Jul 19 | 1 |
59 | 27209475 | In silico evaluation, molecular docking and QSAR analysis of quinazoline-based EGFR-T790M inhibitors. | 2016 Aug | 2 |
60 | 27387355 | 6-Oxooxazolidine-quinazolines as noncovalent inhibitors with the potential to target mutant forms of EGFR. | 2016 Aug 15 | 2 |
61 | 27491023 | Tyrosine Kinase Inhibitors. 20. Optimization of Substituted Quinazoline and Pyrido[3,4-d]pyrimidine Derivatives as Orally Active, Irreversible Inhibitors of the Epidermal Growth Factor Receptor Family. | 2016 Sep 8 | 2 |
62 | 25092264 | Positional isomerization of a non-cleavable combi-molecule dramatically altered tumor cell response profile. | 2015 Feb | 2 |
63 | 25462282 | Design, synthesis and biological evaluation of 6-(nitroimidazole-1H-alkyloxyl)-4-anilinoquinazolines as efficient EGFR inhibitors exerting cytotoxic effects both under normoxia and hypoxia. | 2015 Jan 7 | 1 |
64 | 25910402 | Quinazoline derivatives as anticancer drugs: a patent review (2011 - present). | 2015 Jul | 2 |
65 | 25948633 | EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors. | 2015 Sep 1 | 2 |
66 | 26238612 | Novel quinazoline derivatives exhibit antitumor activity by inhibiting JAK2/STAT3. | 2015 Oct | 2 |
67 | 26310890 | Structure-activity study of quinazoline derivatives leading to the discovery of potent EGFR-T790M inhibitors. | 2015 Sep 18 | 1 |
68 | 24269963 | The ErbB/HER family of protein-tyrosine kinases and cancer. | 2014 Jan | 1 |
69 | 24387079 | Epidermal growth factor receptor inhibitors: a patent review (2010 - present). | 2014 Mar | 1 |
70 | 24928736 | ErbB/HER protein-tyrosine kinases: Structures and small molecule inhibitors. | 2014 Sep | 1 |
71 | 24953979 | Novel therapeutic strategies for patients with NSCLC that do not respond to treatment with EGFR inhibitors. | 2014 Sep | 1 |
72 | 24992720 | QSAR-based models for designing quinazoline/imidazothiazoles/pyrazolopyrimidines based inhibitors against wild and mutant EGFR. | 2014 | 5 |
73 | 25305687 | Optimization of gefitinib analogues with potent anticancer activity. | 2014 Nov 15 | 1 |
74 | 25409491 | A chemical tuned strategy to develop novel irreversible EGFR-TK inhibitors with improved safety and pharmacokinetic profiles. | 2014 Dec 11 | 1 |
75 | 23847159 | 6-Aryl and heterocycle quinazoline derivatives as potent EGFR inhibitors with improved activity toward gefitinib-sensitive and -resistant tumor cell lines. | 2013 Sep | 1 |
76 | 23959266 | ZRX1, the first EGFR inhibitor-capecitabine based combi-molecule, requires carboxylesterase-mediated hydrolysis for optimal activity. | 2013 Dec | 1 |
77 | 26417222 | Combined 3D-QSAR modeling and molecular docking study on multi-acting quinazoline derivatives as HER2 kinase inhibitors. | 2013 | 2 |
78 | 21764376 | EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications. | 2012 Jan | 2 |
79 | 22043991 | Recent developments of small molecule EGFR inhibitors based on the quinazoline core scaffolds. | 2012 May | 2 |
80 | 22169601 | Novel inhibitors of epidermal growth factor receptor: (4-(Arylamino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)(1H-indol-2-yl)methanones and (1H-indol-2-yl)(4-(phenylamino)thieno[2,3-d]pyrimidin-6-yl)methanones. | 2012 Jan 1 | 1 |
81 | 22309911 | Synthesis and biological evaluation of quinazoline and quinoline bearing 2,2,6,6-tetramethylpiperidine-N-oxyl as potential epidermal growth factor receptor(EGFR) tyrosine kinase inhibitors and EPR bio-probe agents. | 2012 Mar | 2 |
82 | 22421369 | Enhancement of the cytotoxic potential of the mixed EGFR and DNA-targeting 'combi-molecule' ZRBA1 against human solid tumour cells by a bis-quinazoline-based drug design approach. | 2012 Jun | 5 |
83 | 22818848 | Novel oxazolo[4,5-g]quinazolin-2(1H)-ones: dual inhibitors of EGFR and Src protein tyrosine kinases. | 2012 Sep | 1 |
84 | 22901387 | Discovery of 6-substituted 4-anilinoquinazolines with dioxygenated rings as novel EGFR tyrosine kinase inhibitors. | 2012 Sep 15 | 2 |
85 | 22959248 | Synthesis and biological evaluation of crown ether fused quinazoline analogues as potent EGFR inhibitors. | 2012 Oct 1 | 1 |
86 | 21254978 | Novel substituted quinazolines for potent EGFR tyrosine kinase inhibitors. | 2011 | 1 |
87 | 21294849 | Synthesis and studies on three-compartment flavone-containing combi-molecules designed to target EGFR, DNA, and MEK. | 2011 May | 1 |
88 | 21677478 | [Erlotinib in non-small cell lung cancer]. | 2011 Jun | 1 |
89 | 21789172 | AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo. | 2011 | 1 |
90 | 21811593 | Prediction of inhibitory activity of epidermal growth factor receptor inhibitors using grid search-projection pursuit regression method. | 2011 | 2 |
91 | 20222923 | Refractory aggressive keratoacanthoma centrifugum marginatum of the scalp controlled with the epidermal growth factor receptor inhibitor erlotinib. | 2010 Sep | 1 |
92 | 20599299 | Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study. | 2010 Sep | 1 |
93 | 20627376 | New substituted 4-arylaminoquinazolines as potent inhibitors of breast tumor cell lines: in vitro and docking experiments. | 2010 Sep | 1 |
94 | 20657425 | Receptor-based virtual screening of EGFR kinase inhibitors from the NCI diversity database. | 2010 Jun 4 | 1 |
95 | 24825983 | 3d QSAR studies on a series of quinazoline derrivatives as tyrosine kinase (egfr) inhibitor: the k-nearest neighbor molecular field analysis approach. | 2010 Jun | 2 |
96 | 18771819 | Synthesis and in vitro antitumor activities of novel 4-anilinoquinazoline derivatives. | 2009 Jul | 1 |
97 | 19275520 | Synthesis of quinazolines as tyrosine kinase inhibitors. | 2009 Mar | 1 |
98 | 19291100 | Rational design of multitargeted tyrosine kinase inhibitors: a novel approach. | 2009 Apr | 1 |
99 | 18465761 | Allene as an alternative functional group for drug design: effect of C--C multiple bonds conjugated with quinazolines on the inhibition of EGFR tyrosine kinase. | 2008 Jul | 2 |
100 | 18585943 | Homology models of the mutated EGFR and their response towards quinazoline analogues. | 2008 Oct | 1 |