Title : Allene as an alternative functional group for drug design: effect of C--C multiple bonds conjugated with quinazolines on the inhibition of EGFR tyrosine kinase.

Pub. Date : 2008 Jul

PMID : 18465761






2 Functional Relationships(s)
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1 Allene as an alternative functional group for drug design: effect of C--C multiple bonds conjugated with quinazolines on the inhibition of EGFR tyrosine kinase. Quinazolines epidermal growth factor receptor Homo sapiens
2 According to immunoblot analysis, the allenic quinazolines inhibited the EGF-mediated phosphorylation of EGFR and its downstream kinases in A431 cells. Quinazolines epidermal growth factor receptor Homo sapiens