134 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
101 | 18608750 | QSAR of aromatic substances: EGFR inhibitory activity of quinazoline analogues. | 2008 Dec | 1 |
102 | 18688420 | Rhenium and technetium complexes bearing quinazoline derivatives: progress towards a 99mTc biomarker for EGFR-TK imaging. | 2008 Jun 28 | 2 |
103 | 18702009 | Synthesis and characterization of novel quinazoline type inhibitors for mutant and wild-type EGFR and RICK kinases. | 2008 | 2 |
104 | 20477246 | Erlotinib: an EGF receptor tyrosine kinase inhibitor in non-small-cell lung cancer treatment. | 2008 Apr | 1 |
105 | 17404024 | The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses proliferation and invasion of human oral squamous carcinoma cells via p53 independent and MMP, uPAR dependent mechanism. | 2007 Jan | 1 |
106 | 17416531 | Dual irreversible kinase inhibitors: quinazoline-based inhibitors incorporating two independent reactive centers with each targeting different cysteine residues in the kinase domains of EGFR and VEGFR-2. | 2007 Jun 1 | 1 |
107 | 17449254 | Radioiodination of new EGFR inhibitors as potential SPECT agents for molecular imaging of breast cancer. | 2007 Jun 15 | 3 |
108 | 17591829 | Erlotinib in cancer treatment. | 2007 Jun | 1 |
109 | 16275081 | Acryloylamino-salicylanilides as EGFR PTK inhibitors. | 2006 Jan 15 | 1 |
110 | 16480284 | Tyrosine kinase inhibitors. 19. 6-Alkynamides of 4-anilinoquinazolines and 4-anilinopyrido[3,4-d]pyrimidines as irreversible inhibitors of the erbB family of tyrosine kinase receptors. | 2006 Feb 23 | 1 |
111 | 16107496 | Gefitinib (ZD1839) combined with weekly epirubicin in patients with metastatic breast cancer: a phase I study with biological correlate. | 2005 Dec | 1 |
112 | 16336752 | Overview of monoclonal antibodies and small molecules targeting the epidermal growth factor receptor pathway in colorectal cancer. | 2005 Nov | 2 |
113 | 14991862 | Inhibition of cell signaling by the combi-nitrosourea FD137 in the androgen independent DU145 prostate cancer cell line. | 2004 Apr 1 | 2 |
114 | 14997040 | Evaluation of novel epidermal growth factor receptor tyrosine kinase inhibitors. | 2004 Jan | 1 |
115 | 15345335 | Molecular mechanisms of ZD1839-induced G1-cell cycle arrest and apoptosis in human lung adenocarcinoma A549 cells. | 2004 Oct 1 | 1 |
116 | 15469331 | Synthesis of AX7593, a quinazoline-derived photoaffinity probe for EGFR. | 2004 Oct 14 | 1 |
117 | 15475435 | Modulation of DNA repair in vitro after treatment with chemotherapeutic agents by the epidermal growth factor receptor inhibitor gefitinib (ZD1839). | 2004 Oct 1 | 1 |
118 | 12447985 | Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs): simple drugs with a complex mechanism of action? | 2003 Jan | 2 |
119 | 12712332 | Prostate cancer cell proliferation is strongly reduced by the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in vitro on human cell lines and primary cultures. | 2003 Mar | 2 |
120 | 12840799 | Erlotinib (Tarceva): an update on the clinical trial program. | 2003 Jun | 1 |
121 | 12859950 | Achieving selectivity between highly homologous tyrosine kinases: a novel selective erbB2 inhibitor. | 2003 Jul 25 | 2 |
122 | 12923594 | Successful treatment of multifocal bronchioloalveolar cell carcinoma with ZD1839 (Iressa) in two patients. | 2003 Jun | 1 |
123 | 15314969 | Anti-HER therapeutic agents in the treatment of non-small-cell lung cancer. | 2003 | 1 |
124 | 12171571 | 4-anilino-3-quinolinecarbonitriles: an emerging class of kinase inhibitors. | 2002 Sep | 1 |
125 | 11550209 | Effect of an EGF-R selective tyrosine kinase inhibitor and an anti-androgen on LNCaP cells: identification of divergent growth regulatory pathways. | 2001 Sep 15 | 2 |
126 | 11585755 | The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer. | 2001 Oct 1 | 1 |
127 | 12188892 | Structure-based design of novel anticancer agents. | 2001 May | 1 |
128 | 10702262 | Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity. | 2000 Mar 10 | 2 |
129 | 10753475 | Tyrosine kinase inhibitors. 17. Irreversible inhibitors of the epidermal growth factor receptor: 4-(phenylamino)quinazoline- and 4-(phenylamino)pyrido[3,2-d]pyrimidine-6-acrylamides bearing additional solubilizing functions. | 2000 Apr 6 | 2 |
130 | 10815932 | Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. | 2000 May | 1 |
131 | 11129168 | Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy. | 2000 | 1 |
132 | 11129169 | Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents. | 2000 | 1 |
133 | 10632369 | Specificity of alpha-cyano-beta-hydroxy-beta-methyl-n-[4-(trifluoromethoxy)phe nyl]-propenamide as an inhibitor of the epidermal growth factor receptor tyrosine kinase. | 1999 Dec | 1 |
134 | 9287333 | Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site. | 1997 Sep 12 | 7 |