Pub. Date : 2014
PMID : 24992720
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | QSAR-based models for designing quinazoline/imidazothiazoles/pyrazolopyrimidines based inhibitors against wild and mutant EGFR. | Quinazolines | epidermal growth factor receptor | Homo sapiens |
| 2 | The existing quinazoline derivative based drugs used for treating lung cancer that inhibits the wild type of EGFR. | Quinazolines | epidermal growth factor receptor | Homo sapiens |
| 3 | In this study, we have made a systematic attempt to develop QSAR models for designing quinazoline derivatives that could inhibit wild EGFR and imidazothiazoles/pyrazolopyrimidines derivatives against mutant EGFR. | Quinazolines | epidermal growth factor receptor | Homo sapiens |
| 4 | In this study, we have made a systematic attempt to develop QSAR models for designing quinazoline derivatives that could inhibit wild EGFR and imidazothiazoles/pyrazolopyrimidines derivatives against mutant EGFR. | Quinazolines | epidermal growth factor receptor | Homo sapiens |
| 5 | First, we developed models for predicting inhibitors against wild type EGFR by training and testing on dataset containing 128 quinazoline based inhibitors. | Quinazolines | epidermal growth factor receptor | Homo sapiens |