Title : EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications.

Pub. Date : 2012 Jan

PMID : 21764376






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Classic EGFR activating mutations, such as inframe deletions in exon 19 or the Leu858Arg (L858R) point mutation in exon 21 are associated with sensitivity to first generation quinazoline reversible EGFR tyrosine kinase inhibitors (TKIs). Quinazolines epidermal growth factor receptor Homo sapiens
2 Classic EGFR activating mutations, such as inframe deletions in exon 19 or the Leu858Arg (L858R) point mutation in exon 21 are associated with sensitivity to first generation quinazoline reversible EGFR tyrosine kinase inhibitors (TKIs). Quinazolines epidermal growth factor receptor Homo sapiens