Title : 6-Oxooxazolidine-quinazolines as noncovalent inhibitors with the potential to target mutant forms of EGFR.

Pub. Date : 2016 Aug 15

PMID : 27387355






2 Functional Relationships(s)
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1 6-Oxooxazolidine-quinazolines as noncovalent inhibitors with the potential to target mutant forms of EGFR. Quinazolines epidermal growth factor receptor Homo sapiens
2 To address this unmet medical need, we demonstrated a strategy to prepare a hybrid analogue consisting of the oxooxazolidine ring and the quinazoline scaffold and provided alternative noncovalent inhibitors targeting mutant forms of EGFR. Quinazolines epidermal growth factor receptor Homo sapiens