Pub. Date : 2020 Oct
PMID : 33304472
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | EGFR-rich extracellular vesicles derived from highly metastatic nasopharyngeal carcinoma cells accelerate tumour metastasis through PI3K/AKT pathway-suppressed ROS. | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |
2 | Here, we demonstrated that epidermal growth factor receptor (EGFR) was highly expressed in tumour tissues of NPC patients with distant metastases and was associated with a decrease in reactive oxygen species (ROS). | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |
3 | Here, we demonstrated that epidermal growth factor receptor (EGFR) was highly expressed in tumour tissues of NPC patients with distant metastases and was associated with a decrease in reactive oxygen species (ROS). | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |
4 | Here, we demonstrated that epidermal growth factor receptor (EGFR) was highly expressed in tumour tissues of NPC patients with distant metastases and was associated with a decrease in reactive oxygen species (ROS). | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |
5 | Here, we demonstrated that epidermal growth factor receptor (EGFR) was highly expressed in tumour tissues of NPC patients with distant metastases and was associated with a decrease in reactive oxygen species (ROS). | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |
6 | Mechanistically, EGFR-rich EVs-mediated EGFR overexpression down-regulated intracellular ROS levels through the PI3K/AKT pathway, thus promoting the metastatic potential of poorly metastatic NPC cells. | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |
7 | Mechanistically, EGFR-rich EVs-mediated EGFR overexpression down-regulated intracellular ROS levels through the PI3K/AKT pathway, thus promoting the metastatic potential of poorly metastatic NPC cells. | Reactive Oxygen Species | epidermal growth factor receptor | Homo sapiens |