Title : Selective phosphorylation of serine 345 on p47-phox serves as a priming signal of ROS-mediated axonal degeneration.

Pub. Date : 2022 Jun

PMID : 35218706






2 Functional Relationships(s)
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1 We previously reported that reactive oxygen species (ROS) generated by NADPH oxidases induces EGFR-dependent phosphorylation and activation of ZNRF1 ubiquitin ligase in neurons, which promotes neuronal cell death and neurite degeneration. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens
2 We previously reported that reactive oxygen species (ROS) generated by NADPH oxidases induces EGFR-dependent phosphorylation and activation of ZNRF1 ubiquitin ligase in neurons, which promotes neuronal cell death and neurite degeneration. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens