Title : AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.

Pub. Date : 2019 Feb 26

PMID : 30733286






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Mechanistically, ROS triggers AhR nuclear accumulation and activation to promote the transcription of both antioxidant enzymes and the epidermal growth factor receptor (EGFR) ligand, amphiregulin (AREG). Reactive Oxygen Species epidermal growth factor receptor Homo sapiens
2 Mechanistically, ROS triggers AhR nuclear accumulation and activation to promote the transcription of both antioxidant enzymes and the epidermal growth factor receptor (EGFR) ligand, amphiregulin (AREG). Reactive Oxygen Species epidermal growth factor receptor Homo sapiens