Title : NADPH oxidases promote apoptosis by activating ZNRF1 ubiquitin ligase in neurons treated with an exogenously applied oxidant.

Pub. Date : 2016 Mar-Apr

PMID : 27195063






1 Functional Relationships(s)
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1 These results suggest an important role for NADPH oxidase in the initiation/promotion of neuronal degeneration by increasing ROS in close proximity to protein machineries, including those for ZNRF1 and EGFR, thereby promoting neuronal degeneration. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens