Title : p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling.

Pub. Date : 2019

PMID : 31360122






1 Functional Relationships(s)
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1 In contrast, in chemoresistant NSCLC, activated Akt promotes EGFR signaling by the positive feedback loop and suppresses CDDP-induced ROS production and apoptosis. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens