Cisplatin

mitogen-activated protein kinase 14 ; Homo sapiens







94 Article(s)
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51 23299493 Fucoxanthin enhances cisplatin-induced cytotoxicity via NFκB-mediated pathway and downregulates DNA repair gene expression in human hepatoma HepG2 cells. 2013 Jan 8 1
52 23570372 Phosphorylation of eIF2α suppresses cisplatin-induced A549 cell apoptosis via p38 inhibition. 2013 May 2
53 23926438 Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells. 2013 1
54 23933134 Quantitative profiling of tyrosine phosphorylation revealed changes in the activity of the T cell receptor signaling pathway upon cisplatin-induced apoptosis. 2013 Oct 8 3
55 24115572 Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK. 2013 Nov 4
56 24185104 14-3-3σ attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells. 2013 Nov 2
57 21684138 Sulforaphane, a natural constituent of broccoli, prevents cell death and inflammation in nephropathy. 2012 May 3
58 21898549 p38 MAPK activation, JNK inhibition, neoplastic growth inhibition, and increased gap junction communication in human lung carcinoma and Ras-transformed cells by 4-phenyl-3-butenoic acid. 2012 Jan 1
59 22142405 The response of human ectomesenchymal dental pulp stem cells to cisplatin treatment. 2012 May 1
60 22415779 p38 Mitogen-activated protein kinase signaling, ERCC1 expression, and viability of lung cancer cells from never or light smoker patients. 2012 Oct 15 2
61 23019413 Alterations of phosphoproteins in NCI-H526 small cell lung cancer cells involved in cytotoxicity of cisplatin and titanocene Y. 2012 Sep 1
62 21165580 Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells. 2011 Mar 1
63 21320468 Induction of ER stress protects gastric cancer cells against apoptosis induced by cisplatin and doxorubicin through activation of p38 MAPK. 2011 Mar 11 3
64 21803700 Involvement of MAPK phosphatase-1 in dexamethasone-induced chemoresistance in lung cancer. 2011 Aug 1
65 21993003 Oxytocin inhibits NADPH oxidase and P38 MAPK in cisplatin-induced nephrotoxicity. 2011 Oct 1
66 22027747 Expression of NLK and its potential effect in ovarian cancer chemotherapy. 2011 Nov 1
67 22164285 Balance between MKK6 and MKK3 mediates p38 MAPK associated resistance to cisplatin in NSCLC. 2011 5
68 19435873 Inhibition of the met receptor tyrosine kinase signaling enhances the chemosensitivity of glioma cell lines to CDDP through activation of p38 MAPK pathway. 2009 May 2
69 19471112 Cisplatin reduces endothelial cell migration via regulation of type 2-matrix metalloproteinase activity. 2009 2
70 17893873 c-Abl activates p38 MAPK independently of its tyrosine kinase activity: Implications in cisplatin-based therapy. 2008 Jan 15 4
71 18093981 A sensitive flow cytometry-based nucleotide excision repair assay unexpectedly reveals that mitogen-activated protein kinase signaling does not regulate the removal of UV-induced DNA damage in human cells. 2008 Feb 29 1
72 17369856 Upregulation of tissue inhibitor of matrix metalloproteinases-1 confers the anti-invasive action of cisplatin on human cancer cells. 2007 Aug 23 1
73 17504983 Heat shock protein 27 protects L929 cells from cisplatin-induced apoptosis by enhancing Akt activation and abating suppression of thioredoxin reductase activity. 2007 May 15 4
74 17505786 Apoptosis by cisplatin requires p53 mediated p38alpha MAPK activation through ROS generation. 2007 Sep 5
75 17699106 (Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1. 2007 Aug 1
76 16331246 Protection of glioblastoma cells from cisplatin cytotoxicity via protein kinase Ciota-mediated attenuation of p38 MAP kinase signaling. 2006 May 11 5
77 16387351 Acquisition of chemoresistance following discontinuous exposures to cisplatin is associated in ovarian carcinoma cells with progressive alteration of FAK, ERK and p38 activation in response to treatment. 2006 Jun 2
78 16596182 Cellular components involved in the cell death induced by cisplatin in the absence of p53 activation. 2006 May 1
79 16785992 Cisplatin induces PKB/Akt activation and p38(MAPK) phosphorylation of the EGF receptor. 2006 Nov 30 3
80 15496615 The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway. 2005 Feb 1
81 15886300 Sphingosine-1-phosphate lyase regulates sensitivity of human cells to select chemotherapy drugs in a p38-dependent manner. 2005 May 1
82 16052670 Role of stress-activated MAP kinase P38 in cisplatin- and DTT-induced apoptosis of the esophageal carcinoma cell line Eca109. 2005 Aug 7 12
83 15010460 Cisplatin-induced post-translational modification of histones H3 and H4. 2004 May 14 1
84 15102355 p38 MAP kinase: a convergence point in cancer therapy. 2004 Mar 1
85 15386344 Long-term activation of SAPK/JNK, p38 kinase and fas-L expression by cisplatin is attenuated in human carcinoma cells that acquired drug resistance. 2004 Dec 20 9
86 12637505 Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells. 2003 May 23 10
87 12697749 AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. 2003 Jun 27 4
88 12821934 Role of the p38 MAPK pathway in cisplatin-based therapy. 2003 Jun 26 9
89 12824923 Enhanced sensitivity to cis-diamminedichloroplatinum(II) of a human carcinoma cell line with mutated p53 gene by cyclin-dependent kinase inhibitor p21(WAF1) expression. 2003 Mar 1
90 30147474 Activation of the JNK/SAPK and P38 Mitogen-Activated Protein Kinase Signaling Pathways Sensitize Tumor Cells to Cisplatin-Induced Apoptosis. 2001 1
91 11064451 CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin. 2000 Oct 26 1
92 11095975 Cisplatin and UV radiation induce activation of the stress-activated protein kinase p38gamma in human melanoma cells. 2000 Nov 30 1
93 9926932 ASK1 mediates apoptotic cell death induced by genotoxic stress. 1999 Jan 7 2
94 8798604 Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms. 1996 Sep 27 1