Title : 14-3-3σ attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells.

Pub. Date : 2013 Nov

PMID : 24185104






2 Functional Relationships(s)
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1 14-3-3sigma attenuates RhoGDI2-induced cisplatin resistance through activation of Erk and p38 in gastric cancer cells. Cisplatin mitogen-activated protein kinase 14 Homo sapiens
2 We also found that the phosphorylation levels of Erk and p38 kinases significantly decreased in RhoGDI2-overexpressing SNU-484 cells and recovered after 14-3-3sigma expression, and that decreased activities of these kinases were critical for RhoGDI2-induced cisplatin resistance. Cisplatin mitogen-activated protein kinase 14 Homo sapiens