Title : Rapidly Progressing Urothelial Carcinoma Due to a Rare TP53 (p.Arg110Pro) Mutation: A Case Report and Review of the Literature.

Pub. Date : 2021

PMID : 33907694






1 Functional Relationships(s)
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1 Knowing that bladder cancer cell lines that lack TP53 are more resistant to cisplatin and because the tumor lacked any other DNA mutation, this patient may have been a candidate for upfront surgery without neoadjuvant chemotherapy. Cisplatin tumor protein p53 Homo sapiens