Title : Cisplatin Chemotherapy and Cochlear Damage: Otoprotective and Chemosensitization Properties of Polyphenols.

Pub. Date : 2021 Dec 17

PMID : 34731023






1 Functional Relationships(s)
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1 Recent Advances: Cisplatin ototoxicity results from several mechanisms, including: redox imbalance caused by reactive oxygen species (ROS) production and lipid peroxidation, activation of inflammation, p53 and its downstream pathways that culminate in apoptosis. Cisplatin tumor protein p53 Homo sapiens