Title : Blockade of TRIM59 enhances esophageal cancer cell chemosensitivity to cisplatin by upregulating p53.

Pub. Date : 2021 Jan

PMID : 33240412






4 Functional Relationships(s)
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1 Blockade of TRIM59 enhances esophageal cancer cell chemosensitivity to cisplatin by upregulating p53. Cisplatin tumor protein p53 Homo sapiens
2 At the molecular level, TRIM59 was indicated to be an E3 putative ubiquitin ligase that targeted the p53 protein, leading to increased degradation of p53, which resulted in decreased chemosensitivity to cisplatin. Cisplatin tumor protein p53 Homo sapiens
3 At the molecular level, TRIM59 was indicated to be an E3 putative ubiquitin ligase that targeted the p53 protein, leading to increased degradation of p53, which resulted in decreased chemosensitivity to cisplatin. Cisplatin tumor protein p53 Homo sapiens
4 The results indicated a relationship between TRIM59, p53 and the chemosensitivity of cisplatin. Cisplatin tumor protein p53 Homo sapiens