Pub. Date : 2021 Oct 29
PMID : 34769213
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The Role of TP53 in Cisplatin Resistance in Mediastinal and Testicular Germ Cell Tumors. | Cisplatin | tumor protein p53 | Homo sapiens |
2 | The full knock-out of TP53 in 2102Ep and resistant NCCIT resulted in an increase in cisplatin resistance, suggesting a contributing role for P53, even in NCCIT, in which P53 had been reported to be non-functional. | Cisplatin | tumor protein p53 | Homo sapiens |
3 | The full knock-out of TP53 in 2102Ep and resistant NCCIT resulted in an increase in cisplatin resistance, suggesting a contributing role for P53, even in NCCIT, in which P53 had been reported to be non-functional. | Cisplatin | tumor protein p53 | Homo sapiens |
4 | The full knock-out of TP53 in 2102Ep and resistant NCCIT resulted in an increase in cisplatin resistance, suggesting a contributing role for P53, even in NCCIT, in which P53 had been reported to be non-functional. | Cisplatin | tumor protein p53 | Homo sapiens |
5 | In conclusion, these results suggest that TP53 mutations contribute to the cisplatin-resistant phenotype of mediastinal GCTs and, therefore, are a potential candidate for targeted treatment. | Cisplatin | tumor protein p53 | Homo sapiens |