Pub. Date : 2022 Jun
PMID : 35487028
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We observed that both p53 (p = 0.0006) and Delta40p53 (p = 0.0014) induced apoptosis in cisplatin-treated SiHa cells; however in cisplatin-treated HeLa cells, only p53 induced apoptosis (p = 0.0029). | Cisplatin | tumor protein p53 | Homo sapiens |
2 | We observed that both p53 (p = 0.0006) and Delta40p53 (p = 0.0014) induced apoptosis in cisplatin-treated SiHa cells; however in cisplatin-treated HeLa cells, only p53 induced apoptosis (p = 0.0029). | Cisplatin | tumor protein p53 | Homo sapiens |
3 | Our findings suggest a possible therapeutic application for the combining of p53 or Delta40p53 with cisplatin to induce an increased apoptosis of cancer cells expressing E6 isoforms from HPV-16. | Cisplatin | tumor protein p53 | Homo sapiens |