| 1 |
33567038 | Optimizing the effective doses of mitomycin C, 5-fluorouracil, and their combination on cultivated basal cell carcinoma. | 2021 |
1 |
| 2 |
34624459 | Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling. | 2021 Nov 1 |
1 |
| 3 |
31871844 | Significance of TP53 mutation in bladder cancer disease progression and drug selection. | 2019 |
1 |
| 4 |
30091208 | Involvement of Akt in mitomycin C and its analog triggered cytotoxicity in MCF-7 and K562 cancer cells. | 2018 Dec |
7 |
| 5 |
28979810 | Enhancing chemotherapy sensitivity by targeting PcG via the ATM/p53 pathway. | 2017 |
4 |
| 6 |
27323408 | LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis. | 2016 Jul 26 |
2 |
| 7 |
27666201 | Mitomycin C and decarbamoyl mitomycin C induce p53-independent p21WAF1/CIP1 activation. | 2016 Nov |
2 |
| 8 |
25713207 | Induction of human UDP-Glucuronosyltransferase 2B7 gene expression by cytotoxic anticancer drugs in liver cancer HepG2 cells. | 2015 May |
2 |
| 9 |
26004085 | Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo. | 2015 Oct |
1 |
| 10 |
26354682 | Hypoxia Promotes Synergy between Mitomycin C and Bortezomib through a Coordinated Process of Bcl-xL Phosphorylation and Mitochondrial Translocation of p53. | 2015 Dec |
1 |
| 11 |
24675086 | Chromosome breakage induced by the genotoxic agents mitomycin C and cytosine arabinoside is concentration and p53 dependent. | 2014 Jul |
2 |
| 12 |
24789349 | The Fanconi anemia pathway sensitizes to DNA alkylating agents by inducing JNK-p53-dependent mitochondrial apoptosis in breast cancer cells. | 2014 Jul |
3 |
| 13 |
23246812 | Functional characterisation of p53 mutants identified in breast cancers with suboptimal responses to anthracyclines or mitomycin. | 2013 Mar |
2 |
| 14 |
22076446 | Identification of a methylation hotspot in the death receptor Fas/CD95 in bladder cancer. | 2012 Mar |
1 |
| 15 |
22349266 | DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells. | 2012 Jul |
2 |
| 16 |
22420423 | Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer. | 2012 Mar 15 |
2 |
| 17 |
22895172 | Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation. | 2012 Sep 1 |
2 |
| 18 |
20126473 | Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control. | 2010 Feb |
4 |
| 19 |
20479887 | Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents. | 2010 May 7 |
2 |
| 20 |
20536192 | DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1. | 2010 Jul 19 |
3 |
| 21 |
20798760 | Differential toxicity of DNA adducts of mitomycin C. | 2010 Jul 29 |
2 |
| 22 |
18202783 | Asynchronous DNA replication detected by fluorescence in situ hybridisation as a possible indicator of genetic damage in human lymphocytes. | 2008 Feb |
1 |
| 23 |
18224251 | Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis. | 2008 Mar-Apr |
2 |
| 24 |
18559532 | Human T-cell leukemia virus I tax protein sensitizes p53-mutant cells to DNA damage. | 2008 Jun 15 |
1 |
| 25 |
18571879 | Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes. | 2008 Aug 15 |
1 |
| 26 |
18647660 | Differential expression of TP53 associated genes in Fanconi anemia cells after mitomycin C and hydroxyurea treatment. | 2008 Oct 30 |
2 |
| 27 |
18697203 | Kinetics of repression by modified p53 on the PDGF beta-receptor promoter. | 2008 Nov 1 |
1 |
| 28 |
18806879 | Mechanism of mitomycin-induced apoptosis in cultured corneal endothelial cells. | 2008 Sep 15 |
1 |
| 29 |
17372198 | p53 targets identified by protein expression profiling. | 2007 Mar 27 |
2 |
| 30 |
17530733 | Mitomycin-DNA adducts induce p53-dependent and p53-independent cell death pathways. | 2007 Jun 15 |
5 |
| 31 |
16019139 | Mitomycin C induces apoptosis via Fas/FasL dependent pathway and suppression of IL-18 in cervical carcinoma cells. | 2006 Jun 8 |
1 |
| 32 |
15608686 | hTERT antagonizes p53-induced apoptosis independently of telomerase activity. | 2005 Feb 17 |
1 |
| 33 |
15774934 | Adenoviral p53 gene transfer inhibits human Tenon's capsule fibroblast proliferation. | 2005 Apr |
1 |
| 34 |
15908423 | A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells. | 2005 Jul 22 |
1 |
| 35 |
16186332 | Mitomycin-C induces the apoptosis of human Tenon's capsule fibroblast by activation of c-Jun N-terminal kinase 1 and caspase-3 protease. | 2005 Oct |
1 |
| 36 |
15183489 | P53-independent thermosensitization by mitomycin C in human non-small-cell lung cancer cells. | 2004 Jul 1 |
3 |
| 37 |
15199132 | DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX. | 2004 Jul |
3 |
| 38 |
15208667 | p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress. | 2004 Aug 19 |
1 |
| 39 |
12468545 | Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53. | 2003 Feb 14 |
2 |
| 40 |
12807744 | Hypoxia induces p53 through a pathway distinct from most DNA-damaging and stress-inducing agents. | 2003 Jul |
1 |
| 41 |
14654539 | TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer. | 2003 Nov 15 |
2 |
| 42 |
11997093 | Expression of the chicken homologue of the mouse double minute 2 gene. | 2002 Apr 12 |
1 |
| 43 |
11172593 | p53 in SV40-transformed DNA-damaged human cells binds to its cognate sequence but fails to transactivate target genes. | 2001 Feb |
1 |
| 44 |
11223035 | Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents. | 2001 Feb 16 |
2 |
| 45 |
11299739 | Correlation of immunohistochemical p53 labeling index with inhibition rate in chemosensitivity test in gastric and colon cancer. | 2001 Jan-Feb |
1 |
| 46 |
11313875 | Evidence that wild-type p53 in neuroblastoma cells is in a conformation refractory to integration into the transcriptional complex. | 2001 Mar 15 |
2 |
| 47 |
11405176 | Mitomycin C and cisplatin enhanced the antitumor activity of p53-expressing adenovirus in cervical cancer cells. | 2001 |
1 |
| 48 |
11462153 | Mechanism of growth inhibitory effect of Mitomycin-C on cultured human retinal pigment epithelial cells: apoptosis and cell cycle arrest. | 2001 Mar |
1 |
| 49 |
11562347 | Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2. | 2001 Sep 15 |
1 |
| 50 |
11585319 | Specific features of apoptosis in human lens epithelial cells induced by mitomycin C in vitro. | 2001 Aug |
1 |