Pub. Date : 2012 Jul
PMID : 22349266
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | When treated with mitomycin C, p53-deficient cells, but not p53-expressing cells, showed a marked increase in ceramide levels. | Mitomycin | tumor protein p53 | Homo sapiens |
2 | When inhibition of UGCG and treatment with mitomycin C were combined, p53-deficient, but not p53-expressing cells, showed a significant increase in cell death, suggesting that the regulation of sphingolipid metabolism could be used to sensitize cells to chemotherapeutic drugs. | Mitomycin | tumor protein p53 | Homo sapiens |