Title : Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control.

Pub. Date : 2010 Feb

PMID : 20126473






4 Functional Relationships(s)
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Protein Name
Organism
1 Our study showed that p53 mitochondrial translocation was found in mitomycin C (MMC)-treated HepG2. Mitomycin tumor protein p53 Homo sapiens
2 Our study showed that p53 mitochondrial translocation was found in mitomycin C (MMC)-treated HepG2. Mitomycin tumor protein p53 Homo sapiens
3 In the low-dose MMC treatment, the increased mitochondrial p53, Bcl-xL, and Bcl-2 could attenuate apoptosis. Mitomycin tumor protein p53 Homo sapiens
4 However, in the high-dose MMC treatment, only the p53 translocated to the mitochondria and resulted in apoptosis progression. Mitomycin tumor protein p53 Homo sapiens