Pub. Date : 2012 Mar 15
PMID : 22420423
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer. | Mitomycin | tumor protein p53 | Homo sapiens |
2 | CONCLUSIONS: Our data indicate loss of function of the ATM-Chk2-p53 cascade to be strongly associated with resistance to anthracycline/mitomycin-containing chemotherapy in breast cancer. | Mitomycin | tumor protein p53 | Homo sapiens |