Pub. Date : 2010 May 7
PMID : 20479887
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Camptothecin is a reported inhibitor of HIF-1alpha translation, while mitomycin C has been reported to induce p53-dependent HIF-1alpha degradation. | Mitomycin | tumor protein p53 | Homo sapiens |
2 | In this study we demonstrate that the inhibitory effect of mitomycin C on HIF-1alpha protein expression is not dependent on p53 and protein degradation, but also involves HIF-1alpha translational regulation. | Mitomycin | tumor protein p53 | Homo sapiens |