Title : Ligand-dependent interaction of the glucocorticoid receptor with p53 enhances their degradation by Hdm2.

Pub. Date : 2001 Sep 15

PMID : 11562347






1 Functional Relationships(s)
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1 Dexamethasone (Dex) stimulates the degradation of endogenous GR and p53 by the proteasome pathway in HUVEC under hypoxia and mitomycin C treatments, and also in hepatoma cells (HepG2) under normoxia. Mitomycin tumor protein p53 Homo sapiens