Title : Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents.

Pub. Date : 2001 Feb 16

PMID : 11223035






2 Functional Relationships(s)
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1 In this report, the DNA alkylating agents mitomycin C (MMC) and methylmethane sulfonate (MMS), as well as UV radiation, stabilized p53 in a manner independent of phosphorylation in p53 N-terminus. Mitomycin tumor protein p53 Homo sapiens
2 In this report, the DNA alkylating agents mitomycin C (MMC) and methylmethane sulfonate (MMS), as well as UV radiation, stabilized p53 in a manner independent of phosphorylation in p53 N-terminus. Mitomycin tumor protein p53 Homo sapiens