Doxorubicin

tumor protein p53 ; Homo sapiens







715 Article(s)
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1 34126912 Novel Benzyloxyphenyl Pyrimidine-5-Carbonitrile Derivatives as Potential Apoptotic Antiproliferative Agents. 2022 1
2 34562089 The Protective Effect of Natural Compounds on Doxorubicin-Induced Cardiotoxicity via Nicotinamide Adenine Dinucleotide Phosphate Oxidase Inhibition. 2022 Mar 3 2
3 34728188 Synthesis of biocompatible nanocrystalline cellulose against folate receptors as a novel carrier for targeted delivery of doxorubicin. 2022 Jan 5 2
4 34783124 Ginsenoside RG1 augments doxorubicin-induced apoptotic cell death in MDA-MB-231 breast cancer cell lines. 2022 Jan 1
5 34871862 miR-197-5p increases Doxorubicin-mediated anticancer cytotoxicity of HT1080 fibrosarcoma cells by decreasing drug efflux. 2022 Jan 2
6 34903608 Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression. 2022 Feb 1 1
7 35053211 Cancer-Related Intracellular Signalling Pathways Activated by DOXorubicin/Cyclodextrin-Graphene-Based Nanomaterials. 2022 Jan 1 1
8 35053325 Transient Exposure of Endothelial Cells to Doxorubicin Leads to Long-Lasting Vascular Endothelial Growth Factor Receptor 2 Downregulation. 2022 Jan 8 1
9 35078992 Correction: Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response. 2022 Jan 25 1
10 35202675 Suppression of the doxorubicin response by hypoxia-inducible factor-1α is strictly dependent on oxygen concentrations under hypoxic conditions. 2022 Apr 5 1
11 35223843 Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy. 2022 1
12 35311459 Compound cellular stress maximizes apoptosis independently of p53 in glioblastoma. 2022 Jun 3
13 35419287 Propofol Inhibits Proliferation and Augments the Anti-Tumor Effect of Doxorubicin and Paclitaxel Partly Through Promoting Ferroptosis in Triple-Negative Breast Cancer Cells. 2022 1
14 35421634 BAK plays a key role in A-1331852-induced apoptosis in senescent chondrocytes. 2022 Jun 18 1
15 35511749 A high-throughput screening platform identifies novel combination treatments for Malignant Peripheral Nerve Sheath Tumors. 2022 May 5 1
16 35551917 Resolvin E1 attenuates doxorubicin-induced endothelial senescence by modulating NLRP3 inflammasome activation. 2022 Jul 1
17 33528639 Correction to: Nutlin-3 cooperates with doxorubicin to induce apoptosis of human hepatocellular carcinoma cells through p53 or p73 signaling pathways. 2021 Nov 1
18 33591455 Differential sensitivity of renal carcinoma cells to doxorubicin and epigenetic therapeutics depends on the genetic background. 2021 Jun 2
19 33738256 Chidamide Combined With Doxorubicin Induced p53-Driven Cell Cycle Arrest and Cell Apoptosis Reverse Multidrug Resistance of Breast Cancer. 2021 1
20 33767588 miR-26b enhances the sensitivity of hepatocellular carcinoma to Doxorubicin via USP9X-dependent degradation of p53 and regulation of autophagy. 2021 3
21 33915913 Heterogeneities in Cell Cycle Checkpoint Activation Following Doxorubicin Treatment Reveal Targetable Vulnerabilities in TP53 Mutated Ultra High-Risk Neuroblastoma Cell Lines. 2021 Apr 1 2
22 33925586 Chromatin-Directed Proteomics Identifies ZNF84 as a p53-Independent Regulator of p21 in Genotoxic Stress Response. 2021 Apr 27 1
23 34122059 Doxorubicin/Nucleophosmin Binding Protein-Conjugated Nanoparticle Enhances Anti-leukemia Activity in Acute Lymphoblastic Leukemia Cells in vitro and in vivo. 2021 1
24 34315513 Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases. 2021 Jul 27 1
25 34365455 Engineered Aging Cardiac Tissue Chip Model for Studying Cardiovascular Disease. 2021 Aug 6 1
26 34395436 Integrated Chromatin Accessibility and Transcriptome Landscapes of Doxorubicin-Resistant Breast Cancer Cells. 2021 1
27 34504568 Role of C5a and C5aR in doxorubicin-induced cardiomyocyte senescence. 2021 Oct 1
28 34681897 Suppression of Estrogen Receptor Alpha Inhibits Cell Proliferation, Differentiation and Enhances the Chemosensitivity of P53-Positive U2OS Osteosarcoma Cell. 2021 Oct 18 2
29 34912912 Evaluation of cytotoxicity and anticancer activity of kombucha and doxorubicin combination therapy on colorectal cancer cell line HCT-116. 2021 1
30 34948101 Poly(C)-binding Protein 2 Regulates the p53 Expression via Interactions with the 5'-Terminal Region of p53 mRNA. 2021 Dec 10 1
31 31073076 Therapeutic targeting of mutant p53 in pediatric acute lymphoblastic leukemia. 2020 Jan 1
32 31841768 Towards the overcoming of anticancer drug resistance mediated by p53 mutations. 2020 Mar 1
33 31892970 Recombinant Dual-target MDM2/MDMX Inhibitor Reverses Doxorubicin Resistance through Activation of the TAB1/TAK1/p38 MAPK Pathway in Wild-type p53 Multidrug-resistant Breast Cancer Cells. 2020 2
34 31923941 A stimuli-responsive combination therapy for recovering p53-inactivation associated drug resistance. 2020 Mar 4
35 32054357 Senescent Colon and Breast Cancer Cells Induced by Doxorubicin Exhibit Enhanced Sensitivity to Curcumin, Caffeine, and Thymoquinone. 2020 Jan-Dec 2
36 32093041 BTG4 is A Novel p53 Target Gene That Inhibits Cell Growth and Induces Apoptosis. 2020 Feb 19 1
37 32297602 Sensitive and selective monitoring of the DNA damage-induced intracellular p21 protein and unraveling the role of the p21 protein in DNA repair and cell apoptosis by surface plasmon resonance. 2020 May 21 2
38 32330121 Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21WAF1-PKCζ pathway in p16INK4a-silenced cells. 2020 Apr 24 1
39 32391420 Protective role of p53 in doxorubicin-induced cardiomyopathy as a mitochondrial disease. 2020 5
40 32478947 Cell cycle arrest and apoptosis are not dependent on p53 prior to p53-dependent embryonic stem cell differentiation. 2020 Sep 2
41 32505665 Doxorubicin chemotherapy-induced "chemo-brain": Meta-analysis. 2020 Aug 15 1
42 32528731 Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells. 2020 4
43 32712543 The carotenoid fucoxanthin can sensitize multidrug resistant cancer cells to doxorubicin via induction of apoptosis, inhibition of multidrug resistance proteins and metabolic enzymes. 2020 Oct 1
44 32825184 HP1γ Sensitizes Cervical Cancer Cells to Cisplatin through the Suppression of UBE2L3. 2020 Aug 19 3
45 32919690 Folic acid-modified bovine serum albumin nanoparticles with doxorubicin and chlorin e6 for effective combinational chemo-photodynamic therapy. 2020 Dec 1
46 32960902 Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts. 2020 3
47 33001126 Fabrication of aminated poly(glycidyl methacrylate)-based polymers for co-delivery of anticancer drugs and the p53 gene. 2020 Oct 28 8
48 33091670 Novel 1,2,4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity. 2020 Dec 1
49 33121131 O-GlcNAc Transferase Inhibitor Synergistically Enhances Doxorubicin-Induced Apoptosis in HepG2 Cells. 2020 Oct 27 1
50 33137557 Design and synthesis of new pyranoquinolinone heteroannulated to triazolopyrimidine of potential apoptotic antiproliferative activity. 2020 Dec 1