Doxorubicin

tumor protein p53 ; Homo sapiens







715 Article(s)
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51 33205006 Gb3-cSrc complex in glycosphingolipid-enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β-catenin-activated RNA methylation. 2020 Nov 1
52 33425912 EGCG Enhanced the Anti-tumor Effect of Doxorubicine in Bladder Cancer via NF-κB/MDM2/p53 Pathway. 2020 4
53 30254375 TC2N, a novel oncogene, accelerates tumor progression by suppressing p53 signaling pathway in lung cancer. 2019 Jul 1
54 30387173 P65-mediated miR-590 inhibition modulates the chemoresistance of osteosarcoma to doxorubicin through targeting wild-type p53-induced phosphatase 1. 2019 Apr 2
55 30591552 Disruption of the Rbm38-eIF4E Complex with a Synthetic Peptide Pep8 Increases p53 Expression. 2019 Feb 15 2
56 30622244 Erythropoietin inhibits chemotherapy-induced cell death and promotes a senescence-like state in leukemia cells. 2019 Jan 8 1
57 30656973 MDM2 antagonist-loaded targeted micelles in combination with doxorubicin: effective synergism against human glioblastoma via p53 re-activation. 2019 Jun - Jul 1
58 30666159 Peptidylarginine deiminase 4 overexpression resensitizes MCF-7/ADR breast cancer cells to adriamycin via GSK3β/p53 activation. 2019 1
59 30667081 Targeting mutant TP53 as a potential therapeutic strategy for the treatment of osteosarcoma. 2019 Mar 1
60 30678901 Synthesis and evaluation of the antiproliferative efficacy of BRM270 phytocomposite nanoparticles against human hepatoma cancer cell lines. 2019 Apr 1
61 30683849 SETD3 is a positive regulator of DNA-damage-induced apoptosis. 2019 Jan 25 1
62 30728290 Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity. 2019 Feb 6 1
63 30760381 PRR11 and SKA2 gene pair is overexpressed and regulated by p53 in breast cancer. 2019 Feb 1
64 30778138 On-chip combined radiotherapy and chemotherapy testing on soft-tissue sarcoma spheroids to study cell death using flow cytometry and clonogenic assay. 2019 Feb 18 1
65 30868056 Histone deacetylase 2 is involved in DNA damage-mediated cell death of human osteosarcoma cells through stimulation of the ATM/p53 pathway. 2019 Mar 2
66 30883017 Delanzomib, a novel proteasome inhibitor, sensitizes breast cancer cells to doxorubicin-induced apoptosis. 2019 Apr 1
67 30960044 A Polycationic Brush Mediated Co-Delivery of Doxorubicin and Gene for Combination Therapy. 2019 Jan 3 3
68 30971831 Metformin prevention of doxorubicin resistance in MCF-7 and MDA-MB-231 involves oxidative stress generation and modulation of cell adaptation genes. 2019 Apr 10 2
69 31022952 p53-Dependent Apoptotic Effect of Puromycin via Binding of Ribosomal Protein L5 and L11 to MDM2 and its Combination Effect with RITA or Doxorubicin. 2019 Apr 24 2
70 31081062 INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4. 2019 Jun 1
71 31183995 Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro. 2019 Aug 1
72 31231550 Transcriptomic profiling reveals p53 as a key regulator of doxorubicin-induced cardiotoxicity. 2019 2
73 31235998 MiR-34a overexpression enhances the inhibitory effect of doxorubicin on HepG2 cells. 2019 Jun 14 2
74 31244936 Lgr5-mediated p53 Repression through PDCD5 leads to doxorubicin resistance in Hepatocellular Carcinoma. 2019 2
75 31319070 Nicorandil prevents doxorubicin-induced human umbilical vein endothelial cell apoptosis. 2019 Sep 15 1
76 31340166 Doxorubicin and liposomal doxorubicin induce senescence by enhancing nuclear factor kappa B and mitochondrial membrane potential. 2019 Sep 1 1
77 31346036 Abrogation of FBW7α-dependent p53 degradation enhances p53's function as a tumor suppressor. 2019 Sep 6 1
78 31366086 Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation. 2019 Jul 30 2
79 31417274 Long noncoding RNA LINC-PINT promotes proliferation through EZH2 and predicts poor prognosis in clear cell renal cell carcinoma. 2019 2
80 31480541 DMPK is a New Candidate Mediator of Tumor Suppressor p53-Dependent Cell Death. 2019 Sep 1 2
81 31482012 Transcription-independent and -dependent p53-mediated apoptosis in response to genotoxic and non-genotoxic stress. 2019 6
82 31488712 p53 prevents doxorubicin cardiotoxicity independently of its prototypical tumor suppressor activities. 2019 Sep 24 1
83 31497354 Wild-type TP53 defined gamma-secretase inhibitor sensitivity and synergistic activity with doxorubicin in GSCs. 2019 3
84 31503014 Antitumor effect of a short peptide on p53-null SKOV3 ovarian cancer cells. 2019 Nov 1
85 31511498 Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response. 2019 Sep 11 1
86 31527453 Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells. 2019 Sep 16 1
87 31571866 Tuning the surface coating of IONs toward efficient sonochemical tethering and sustained liberation of topoisomerase II poisons. 2019 1
88 31871844 Significance of TP53 mutation in bladder cancer disease progression and drug selection. 2019 1
89 31976328 Dihydroartemisinin Sensitizes Mutant p53 (R248Q)-Expressing Hepatocellular Carcinoma Cells to Doxorubicin by Inhibiting P-gp Expression. 2019 8
90 32123852 Aspirin ameliorates the long-term adverse effects of doxorubicin through suppression of cellular senescence. 2019 Sep 1
91 28797827 Interaction between mTOR pathway inhibition and autophagy induction attenuates adriamycin-induced vascular smooth muscle cell senescence through decreased expressions of p53/p21/p16. 2018 Aug 2
92 29207086 Tan IIA inhibits H1299 cell viability through the MDM4‑IAP3 signaling pathway. 2018 Feb 2
93 29207090 Long intergenic non‑coding RNA‑p21 mediates cardiac senescence via the Wnt/β‑catenin signaling pathway in doxorubicin-induced cardiotoxicity. 2018 Feb 1
94 29290620 Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis. 2018 Feb 2
95 29352261 Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells. 2018 Jan 19 3
96 29416744 Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer. 2018 Jan 5 1
97 29731965 TP53 and OSBPL10 alterations in diffuse large B-cell lymphoma: prognostic markers identified via exome analysis of cases with extreme prognosis. 2018 Apr 13 2
98 29743236 IDH1 Arg-132 mutant promotes tumor formation through down-regulating p53. 2018 Jun 22 1
99 29772519 p53 and P-glycoprotein influence chemoresistance in hepatocellular carcinoma. 2018 Jun 1 1
100 29775409 Transactivation domain of p53 regulates DNA repair and integrity in human iPS cells. 2018 Sep 1 4