| 1 |
35303539 | Effect of UGT1A4, UGT2B7, UGT2B15, UGT2B17 and ABC1B polymorphisms on lamotrigine metabolism in Danish patients. | 2022 May |
4 |
| 2 |
34423713 | UDP-glucuronosyltransferase 1A4-mediated N2-glucuronidation is the major metabolic pathway of lamotrigine in chimeric NOG-TKm30 mice with humanised-livers. | 2021 Oct |
1 |
| 3 |
32483200 | Influence of genetic variants and antiepileptic drug co-treatment on lamotrigine plasma concentration in Mexican Mestizo patients with epilepsy. | 2020 Dec |
1 |
| 4 |
30168665 | Meta-analysis of the Influence of UGT Genetic Polymorphisms on Lamotrigine Concentration. | 2019 Feb |
2 |
| 5 |
30489548 | Relationship Between UGT1A4 and UGT2B7 Polymorphisms and the Steady-State Plasma Concentrations of Lamotrigine in Patients With Treatment-Resistant Depressive Disorder Receiving Lamotrigine as Augmentation Therapy. | 2019 Feb |
3 |
| 6 |
30086088 | Clinically Relevant Effect of UGT1A4*3 on Lamotrigine Serum Concentration Is Restricted to Postmenopausal Women-A Study Matching Therapeutic Drug Monitoring and Genotype Data From 534 Patients. | 2018 Oct |
4 |
| 7 |
30440130 | [Relationship between UGT1A4 142T>G polymorphism and serum concentration of lamotrigine in Chinese epileptic patients: a meta-analysis]. | 2018 Nov 6 |
2 |
| 8 |
28068583 | No association between non-bullous skin reactions from lamotrigine and heterozygosity of UGT1A4 genetic variants *2(P24T) or *3(L48V) in Norwegian patients. | 2017 Feb |
2 |
| 9 |
25492569 | Frequencies of UGT1A4*2 (P24T) and *3 (L48V) and their effects on serum concentrations of lamotrigine. | 2016 Apr |
3 |
| 10 |
26790665 | Factors that influence the pharmacokinetics of lamotrigine in Japanese patients with epilepsy. | 2016 May |
1 |
| 11 |
27795544 | Association of UGT2B7 and UGT1A4 Polymorphisms with Serum Concentration of Antiepileptic Drugs in Children. | 2016 Oct 31 |
2 |
| 12 |
25922177 | Effects of UGT1A4 genetic polymorphisms on serum lamotrigine concentrations in Chinese children with epilepsy. | 2015 Jun |
1 |
| 13 |
26303110 | Influence of valproic acid concentration and polymorphism of UGT1A4*3, UGT2B7 -161C > T and UGT2B7*2 on serum concentration of lamotrigine in Chinese epileptic children. | 2015 Nov |
2 |
| 14 |
24820767 | Correlation of the UGT1A4 gene polymorphism with serum concentration and therapeutic efficacy of lamotrigine in Han Chinese of Northern China. | 2014 Aug |
2 |
| 15 |
23263737 | Influence of the UGT2B7 -161C>T polymorphism on the population pharmacokinetics of lamotrigine in Thai patients. | 2013 Jun |
1 |
| 16 |
23865846 | Expression and functional relevance of UGT1A4 in a cohort of human drug-resistant epileptic brains. | 2013 Sep |
2 |
| 17 |
21302032 | Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term. | 2011 Jan |
2 |
| 18 |
21487055 | In vitro investigation of human UDP-glucuronosyltransferase isoforms responsible for tacrolimus glucuronidation: predominant contribution of UGT1A4. | 2011 Jul |
2 |
| 19 |
21601426 | The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy. | 2011 Jun |
1 |
| 20 |
21726413 | Effect of common exon variant (p.P364L) on drug glucuronidation by the human UDP-glucuronosyltransferase 1 family. | 2011 Dec |
1 |
| 21 |
20007295 | Glucuronidation of dihydrotestosterone and trans-androsterone by recombinant UDP-glucuronosyltransferase (UGT) 1A4: evidence for multiple UGT1A4 aglycone binding sites. | 2010 Mar |
2 |
| 22 |
20216122 | UGT2B7_-161C>T polymorphism is associated with lamotrigine concentration-to-dose ratio in a multivariate study. | 2010 Apr |
2 |
| 23 |
20692811 | Serum levels of lamotrigine during delivery in mothers and their infants. | 2010 Oct |
2 |
| 24 |
19387891 | Variation in glucuronidation of lamotrigine in human liver microsomes. | 2009 May |
2 |
| 25 |
19487247 | Influence of N-terminal domain histidine and proline residues on the substrate selectivities of human UDP-glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10. | 2009 Sep |
2 |
| 26 |
19546240 | Up-regulation of UDP-glucuronosyltransferase (UGT) 1A4 by 17beta-estradiol: a potential mechanism of increased lamotrigine elimination in pregnancy. | 2009 Sep |
3 |
| 27 |
19845433 | Studies on induction of lamotrigine metabolism in transgenic UGT1 mice. | 2009 Nov |
2 |
| 28 |
17151188 | Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation. | 2007 Mar |
1 |
| 29 |
17430308 | Two case reports of oral ulcers with lamotrigine several weeks after oxcarbazepine withdrawal. | 2007 May |
2 |
| 30 |
17636046 | Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4. | 2007 Oct |
2 |
| 31 |
12404680 | Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes. | 2002 Jul |
1 |
| 32 |
10220490 | Retigabine N-glucuronidation and its potential role in enterohepatic circulation. | 1999 May |
2 |