Pub. Date : 2010 Oct
PMID : 20692811
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | CONCLUSIONS: Our data from the large cohort showed the interindividual variability of umbilical cord/maternal serum concentration ratio in lamotrigine monotherapy caused probably by the different activity of the placental lamotrigine metabolizing enzymes UGT1A4 and 2B7 associated with genetic polymorphism. | Lamotrigine | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
2 | CONCLUSIONS: Our data from the large cohort showed the interindividual variability of umbilical cord/maternal serum concentration ratio in lamotrigine monotherapy caused probably by the different activity of the placental lamotrigine metabolizing enzymes UGT1A4 and 2B7 associated with genetic polymorphism. | Lamotrigine | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |