Title : Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation.

Pub. Date : 2007 Mar

PMID : 17151188






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The levels of induced UGT1A3 gene transcripts in liver and UGT1A4 protein in small intestine correlated with induced lamotrigine glucuronidation activity in these tissues. Lamotrigine UDP glucuronosyltransferase family 1 member A4 Homo sapiens