Pub. Date : 1999 May
PMID : 10220490
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | From the known substrate specificities of UGT1A4 toward lamotrigine and bilirubin and our activity and inhibition data, we conclude that UGT1A4 is a major retigabine N-glucuronosyl transferase in vivo and significantly contributes to the enterohepatic cycling of the drug. | Lamotrigine | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |
| 2 | From the known substrate specificities of UGT1A4 toward lamotrigine and bilirubin and our activity and inhibition data, we conclude that UGT1A4 is a major retigabine N-glucuronosyl transferase in vivo and significantly contributes to the enterohepatic cycling of the drug. | Lamotrigine | UDP glucuronosyltransferase family 1 member A4 | Homo sapiens |