Title : Meta-analysis of the Influence of UGT Genetic Polymorphisms on Lamotrigine Concentration.

Pub. Date : 2019 Feb

PMID : 30168665






2 Functional Relationships(s)
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1 Thus, the objective of this meta-analysis was to analyse the influence of UGT1A4 and UGT2B7 genetic polymorphisms on lamotrigine concentration. Lamotrigine UDP glucuronosyltransferase family 1 member A4 Homo sapiens
2 Through searching, screening, selection, data extraction and quantitative analyses, the influence of UGT1A4 and UGT2B7 genetic polymorphisms on lamotrigine concentration-to-dose ratio (CDR) was assessed by meta-analysis of nine studies. Lamotrigine UDP glucuronosyltransferase family 1 member A4 Homo sapiens