| 1 |
28807675 | Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B. | 2017 Nov |
1 |
| 2 |
26876935 | Effects of 1-cyclohexyl- and 1-cyclohexyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline on dopaminergic spontaneous discharge in nigral neurons of rats. | 2016 Mar |
1 |
| 3 |
20045397 | Manganese neurotoxic time course is not influenced by L-deprenyl systemic treatment: influence of L-deprenyl in manganese neurotoxic time course. | 2010 Mar 4 |
1 |
| 4 |
12871570 | Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor. | 2003 Jul |
1 |
| 5 |
11566147 | 1-Methyl-4-phenyl-pyridinium increases S-adenosyl-L-methionine dependent phospholipid methylation. | 2001 Sep |
2 |
| 6 |
10567696 | 1-Methyl-4-phenyl-2,3-dihydropyridinium is transformed by ubiquinone to the selective nigrostriatal toxin 1-methyl-4-phenylpyridinium. | 1999 Nov 19 |
2 |
| 7 |
9813295 | Differential time courses of exogenous 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine and its metabolite MPP+ in the rat striatum and nucleus accumbens measured using in vivo voltammetry. | 1998 Nov 23 |
1 |
| 8 |
9191089 | Elevated expression of glutathione peroxidase in PC12 cells results in protection against methamphetamine but not MPTP toxicity. | 1997 Jun |
1 |
| 9 |
9274805 | MPTP toxicity in rat striatal slices: dopamine uptake alteration does not appear to be related to lipid peroxidation. | 1997 Sep 26 |
1 |
| 10 |
9396088 | Comparison of key steps in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in rodents. | 1997 Nov |
2 |
| 11 |
7849570 | 1-Methyl-4-phenylpyridinium (MPP+)-induced cell death in PC12 cells: inhibitory effects of several drugs. | 1994 Nov |
2 |
| 12 |
8200437 | In brown Norway rats, MPP+ is accumulated in the nigrostriatal dopaminergic terminals but it is not neurotoxic: a model of natural resistance to MPTP toxicity. | 1994 May |
1 |
| 13 |
8121637 | 1-Methyl-4-phenylpyridinium (MPP+) binds with high affinity to a beta-carboline binding site located on monoamine oxidase type A in rat brain. | 1993 Nov 12 |
2 |
| 14 |
8302304 | Selegiline can mediate neuronal rescue rather than neuronal protection. | 1993 |
1 |
| 15 |
1488908 | [Pharmacology of selegiline (recent considerations)]. | 1992 Sep |
1 |
| 16 |
1912294 | Studies on the in vitro conversion of haloperidol to a potentially neurotoxic pyridinium metabolite. | 1991 Jan-Feb |
4 |
| 17 |
2122806 | Relationships between the mitochondrial transmembrane potential, ATP concentration, and cytotoxicity in isolated rat hepatocytes. | 1990 Nov 1 |
2 |
| 18 |
2126479 | 3-Acetylpyridine results in degeneration of the extrapyramidal and cerebellar motor systems: loss of the dorsolateral striatal dopamine innervation. | 1990 Sep 10 |
2 |
| 19 |
2133093 | Studies on the cytochrome P-450 catalyzed ring alpha-carbon oxidation of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). | 1990 Sep-Oct |
3 |
| 20 |
2298362 | MPTP-induced duodenal ulcers in rat. Prevention by reuptake blockers for serotonin and norepinephrine, but not dopamine. | 1990 Mar |
1 |
| 21 |
2898342 | Quantitative analysis of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism in isolated rat hepatocytes. | 1988 Mar-Apr |
1 |
| 22 |
2970526 | Studies on the metabolism and toxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in cultures of embryonic rat mesencephalon. | 1988 Sep |
1 |
| 23 |
3143167 | MPTP and MPTP analogs induced cell death in cultured rat hepatocytes involving the formation of pyridinium metabolites. | 1988 Nov |
2 |
| 24 |
3171572 | Histochemical localisation of monoamine oxidase A and B in rat brain. | 1988 |
1 |
| 25 |
3264604 | Evaluation of the toxicity of the dopaminergic neurotoxins MPTP and MPP+ in PC12 pheochromocytoma cells: binding and biological studies. | 1988 Dec 5 |
1 |
| 26 |
3102694 | Effects of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine and its metabolite 1-methyl-4-phenylpyridine on acetylcholine synthesis in synaptosomes from rat forebrain. | 1987 Apr |
1 |
| 27 |
3123604 | Selegiline and the prophylaxis of Parkinson's disease. | 1987 |
3 |
| 28 |
3319563 | MPTP: an industrial chemical and contaminant of illicit narcotics stimulates a new era in research on Parkinson's disease. | 1987 Nov |
2 |
| 29 |
3496045 | Comparative toxicity and antioxidant activity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its monoamine oxidase B-generated metabolites in isolated hepatocytes and liver microsomes. | 1987 May 15 |
2 |
| 30 |
3097260 | Primate-rodent 3H-MPTP binding differences, and biotransformation of MPTP to a reactive intermediate in vitro. | 1986 |
1 |
| 31 |
3101671 | Oxidation and enzyme-activated irreversible inhibition of rat liver monoamine oxidase-B by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). | 1986 Dec 1 |
2 |
| 32 |
3487052 | Histochemistry of MPTP oxidation in the rat brain: sites of synthesis of the parkinsonism-inducing toxin MPP+. | 1986 Apr 24 |
3 |
| 33 |
2413402 | Dopaminergic toxicity after the stereotaxic administration of the 1-methyl-4-phenylpyridinium ion (MPP+) to rats. | 1985 Aug 16 |
3 |
| 34 |
2861994 | Studies on the molecular mechanism of bioactivation of the selective nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. | 1985 May-Jun |
2 |
| 35 |
3871853 | Inhibition of types A and B monoamine oxidase by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. | 1985 Mar |
2 |
| 36 |
3872460 | Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. | 1985 Apr |
2 |
| 37 |
3872811 | Further insight into the mode of action of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). | 1985 Apr 22 |
1 |
| 38 |
3876227 | Oxidation by rat brain of N-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) coupled to tetrazolium nitro blue. | 1985 Jul 17 |
1 |
| 39 |
3876242 | Serotonergic conversion of MPTP and dopaminergic accumulation of MPP+. | 1985 Sep 23 |
1 |
| 40 |
3876524 | Participation of brain monoamine oxidase B form in the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: relationship between the enzyme inhibition and the neurotoxicity. | 1985 Jul 31 |
7 |
| 41 |
3878183 | In vivo effect of MPTP on monoamine oxidase activity in mouse striatum. | 1985 Dec 16 |
1 |
| 42 |
3912685 | Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity. | 1985 Dec 18 |
1 |
| 43 |
6332989 | Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors. | 1984 Oct 4-10 |
2 |